| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4845963 | A33 | Activity | = | 1.97 | % | ALA4843576 | % | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | |||
| 2. | ALA4845963 | A33 | Activity | = | 32.74 | % | ALA4843575 | % | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | |||
| 3. | ALA4845963 | A33 | Activity | = | 5.08 | % | ALA4843574 | % | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | |||
| 4. | ALA4845963 | A33 | Activity | = | 38.82 | % | ALA4843573 | % | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | |||
| 5. | ALA4845963 | A33 | F | = | 77.69 | % | ALA4843572 | % | ||||
| 6. | ALA4845963 | A33 | AUC | 0 | ALA4843571 | Not Determined | ||||||
| 7. | ALA4845963 | A33 | AUClast | = | 10442 | ng.hr/ml | ALA4843570 | ng.hr.mL-1 | ||||
| 8. | ALA4845963 | A33 | Tmax | = | 5.33 | hr | ALA4843569 | hr | ||||
| 9. | ALA4845963 | A33 | Cmax | = | 754 | ng/ml | ALA4843568 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA4845963 | A33 | AUC | = | 3127 | ng.hr/ml | ALA4843567 | ng.hr.mL-1 | ||||
| 11. | ALA4845963 | A33 | AUClast | = | 2688 | ng.hr/ml | ALA4843566 | ng.hr.mL-1 | ||||
| 12. | ALA4845963 | A33 | CL | = | 10.8 | ml/min.kg | ALA4843565 | mL.min-1.kg-1 | ||||
| 13. | ALA4845963 | A33 | Vdss | = | 7.18 | L/Kg | ALA4843564 | L.kg-1 | ||||
| 14. | ALA4845963 | A33 | t1/2 | = | 9.35 | hr | ALA4843563 | hr | ||||
| 15. | ALA4845963 | A33 | C0 | = | 758 | ng/ml | ALA4843562 | ng/ml | ||||
| 16. | ALA4845963 | A33 | IC50 | = | 14.8 | uM | ALA4843560 | 4.83 | nM | Homo sapiens | ||
| 17. | ALA4845963 | A33 | IC50 | > | 50 | uM | ALA4843559 | nM | Homo sapiens | |||
| 18. | ALA4845963 | A33 | IC50 | = | 1.56 | uM | ALA4843558 | 5.81 | nM | Homo sapiens | ||
| 19. | ALA4845963 | A33 | IC50 | = | 2.3 | uM | ALA4843557 | 5.64 | nM | Homo sapiens | ||
| 20. | ALA4845963 | A33 | IC50 | = | 6.64 | uM | ALA4843556 | 5.18 | nM | Homo sapiens |
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