Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4846521	9	Drug uptake	=	8100	nmol/Kg	ALA4836469			nmol/Kg
2.	ALA4846521	9	Cp	=	3935	nM	ALA4836468			nM
3.	ALA4846521	9	CLH	=	24.1	ml/min.kg	ALA4836467			mL.min-1.kg-1
4.	ALA4846521	9	IC50	=	30.8	nM	ALA4836466	7.51		nM	Homo sapiens
5.	ALA4846521	9	IC50	=	4.4	nM	ALA4836465	8.36		nM	Homo sapiens
6.	ALA4846521	9	Activity		0		ALA4836464		Non-Toxic
7.	ALA4846521	9	Activity		0		ALA4836463		Non-Toxic
8.	ALA4846521	9	Activity		0		ALA4836462		Active		Mus musculus
9.	ALA4846521	9	Activity		0		ALA4836461		Active		Mus musculus
10.	ALA4846521	9	F	=	59.7	%	ALA4836460			%
11.	ALA4846521	9	AUC	=	27723	nM.hr	ALA4836459		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW	ng.hr.mL-1
12.	ALA4846521	9	Vd	=	1.5	L/Kg	ALA4836458			L.kg-1
13.	ALA4846521	9	CL	=	6.6	ml/kg/min	ALA4836457			mL.min-1.kg-1
14.	ALA4846521	9	CLH	=	79	ml/min.kg	ALA4836456			mL.min-1.kg-1
15.	ALA4846521	9	IC50	=	19	nM	ALA4836455	7.72		nM	Mus musculus
16.	ALA4846521	9	IC50	=	0.9	nM	ALA4836454	9.05		nM	Homo sapiens
17.	ALA4846521	9	IC50	=	1.97	nM	ALA4836453	8.71		nM	Homo sapiens
18.	ALA4846521	9	IC50	=	1.29	nM	ALA4836452	8.89		nM	Homo sapiens