# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4846825 | C1 | Ratio EC50 | = | 3 | ALA4830589 | Homo sapiens | |||||
2. | ALA4846825 | C1 | F | = | 32.5 | % | ALA4830561 | % | ||||
3. | ALA4846825 | C1 | CL | = | 156 | ml/min.kg | ALA4830560 | mL.min-1.kg-1 | ||||
4. | ALA4846825 | C1 | Vdss | = | 17.3 | L/Kg | ALA4830559 | L.kg-1 | ||||
5. | ALA4846825 | C1 | t1/2 | = | 1.41 | hr | ALA4830558 | hr | ||||
6. | ALA4846825 | C1 | t1/2 | = | 1.37 | hr | ALA4830557 | hr | ||||
7. | ALA4846825 | C1 | AUCt | = | 157 | ng.hr/ml | ALA4830556 | ng.hr.mL-1 | ||||
8. | ALA4846825 | C1 | AUCt | = | 104 | ng.hr/ml | ALA4830555 | ng.hr.mL-1 | ||||
9. | ALA4846825 | C1 | Cmax | = | 34.1 | ng/ml | ALA4830554 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA4846825 | C1 | Cmax | = | 75.3 | ng/ml | ALA4830553 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
11. | ALA4846825 | C1 | IC50 | = | 6.36 | nM | ALA4830552 | 8.20 | nM | Homo sapiens |