# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4848032 | 25b | solubility | < | 1 | ug ml-1 | ALA4835965 | ug.mL-1 | ||||
2. | ALA4848032 | 25b | permeability | = | 196 | nm/s | ALA4835964 | nm/s | ||||
3. | ALA4848032 | 25b | permeability | < | 15 | nm/s | ALA4835963 | nm/s | ||||
4. | ALA4848032 | 25b | permeability | = | 192 | nm/s | ALA4835962 | nm/s | ||||
5. | ALA4848032 | 25b | permeability | 0 | ALA4835961 | Not Determined | ||||||
6. | ALA4848032 | 25b | Cmax | = | 35 | nM | ALA4835960 | nM | ||||
7. | ALA4848032 | 25b | Fu | = | 2.3 | % | ALA4835959 | |||||
8. | ALA4848032 | 25b | Cp | = | 40 | nM | ALA4835958 | nM | ||||
9. | ALA4848032 | 25b | F | = | 1 | % | ALA4835957 | % | ||||
10. | ALA4848032 | 25b | Cp | = | 170 | nM | ALA4835956 | nM | ||||
11. | ALA4848032 | 25b | Activity | = | 79 | % | ALA4835954 | % | Callithrix jacchus | |||
12. | ALA4848032 | 25b | Activity | = | 85 | % | ALA4835953 | % | Callithrix jacchus | |||
13. | ALA4848032 | 25b | Activity | = | 87 | % | ALA4835952 | % | Callithrix jacchus | |||
14. | ALA4848032 | 25b | Activity | = | 57 | % | ALA4835951 | % | Callithrix jacchus | |||
15. | ALA4848032 | 25b | IC50 | = | 8.1 | uM | ALA4835950 | 5.09 | nM | Homo sapiens | ||
16. | ALA4848032 | 25b | IC50 | = | 0.06 | nM | ALA4835949 | 10.22 | nM | Homo sapiens | ||
17. | ALA4848032 | 25b | Cmax | = | 96 | nM | ALA4835948 | nM | ||||
18. | ALA4848032 | 25b | Stabilty | = | 75 | % | ALA4835947 | % | ||||
19. | ALA4848032 | 25b | Stabilty | = | 35 | % | ALA4835946 | % | ||||
20. | ALA4848032 | 25b | Stabilty | = | 36 | % | ALA4835945 | % |