# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4848357 | 25b | IC50 | = | 0.4 | ug ml-1 | ALA4831718 | ug.mL-1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
2. | ALA4848357 | 25b | Ratio | > | 16 | ALA4831717 | ||||||
3. | ALA4848357 | 25b | MIC | = | 0.12 | ug ml-1 | ALA4831716 | ug.mL-1 | Mycobacterium tuberculosis | |||
4. | ALA4848357 | 25b | MIC | = | 0.25 | ug ml-1 | ALA4831715 | ug.mL-1 | Mycobacterium tuberculosis | |||
5. | ALA4848357 | 25b | MIC | > | 1.98 | ug ml-1 | ALA4831714 | ug.mL-1 | Mycobacterium tuberculosis | |||
6. | ALA4848357 | 25b | IC50 | > | 30 | ug ml-1 | ALA4831696 | ug.mL-1 | Homo sapiens | |||
7. | ALA4848357 | 25b | IC50 | > | 64 | ug ml-1 | ALA4831695 | ug.mL-1 | Homo sapiens | |||
8. | ALA4848357 | 25b | Stability | = | 52.8 | % | ALA4831694 | % | ||||
9. | ALA4848357 | 25b | t1/2 | = | 32.6 | min | ALA4831693 | hr | ||||
10. | ALA4848357 | 25b | Stability | = | 19 | % | ALA4831692 | % | ||||
11. | ALA4848357 | 25b | t1/2 | = | 12.5 | min | ALA4831691 | hr | ||||
12. | ALA4848357 | 25b | Activity | = | 0.77 | deltalog10CFU | ALA4831690 | deltalog10CFU | Mycobacterium tuberculosis | |||
13. | ALA4848357 | 25b | Activity | = | 4.75 | log10CFU | ALA4831689 | log10CFU | Mycobacterium tuberculosis | |||
14. | ALA4848357 | 25b | Activity | = | 0.93 | deltalog10CFU | ALA4831688 | deltalog10CFU | Mycobacterium tuberculosis | |||
15. | ALA4848357 | 25b | Activity | = | 4.59 | log10CFU | ALA4831687 | log10CFU | Mycobacterium tuberculosis | |||
16. | ALA4848357 | 25b | MIC | = | 0.12 | ug ml-1 | ALA4831684 | ug.mL-1 | ||||
17. | ALA4848357 | 25b | MIC | = | 0.062 | ug ml-1 | ALA4831683 | ug.mL-1 | ||||
18. | ALA4848357 | 25b | MIC | = | 0.03 | ug ml-1 | ALA4831682 | ug.mL-1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
19. | ALA4848357 | 25b | Selectivity Index | > | 2133 | ALA4831681 | ||||||
20. | ALA4848357 | 25b | IC50 | > | 64 | ug ml-1 | ALA4831680 | ug.mL-1 | Chlorocebus sabaeus |