| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4848632 | 79; DSM705 | Activity | 0 | ALA4812788 | Active | Plasmodium falciparum | |||||
| 2. | ALA4848632 | 79; DSM705 | Activity | 0 | ALA4812786 | Active | Plasmodium falciparum | |||||
| 3. | ALA4848632 | 79; DSM705 | fAUC | = | 4.1 | uM.hr | ALA4812784 | uM.hr | ||||
| 4. | ALA4848632 | 79; DSM705 | AUCED90 | = | 36 | uM.hr | ALA4812783 | uM.hr | Plasmodium falciparum | |||
| 5. | ALA4848632 | 79; DSM705 | ED50 | = | 26 | uM | ALA4812782 | uM | Plasmodium falciparum | |||
| 6. | ALA4848632 | 79; DSM705 | EC50 | = | 0.12 | uM | ALA4812781 | 6.92 | nM | Plasmodium vivax | ||
| 7. | ALA4848632 | 79; DSM705 | EC50 | = | 0.12 | uM | ALA4812780 | 6.92 | nM | Plasmodium falciparum | ||
| 8. | ALA4848632 | 79; DSM705 | EC50 | = | 0.011 | uM | ALA4812779 | 7.96 | nM | Plasmodium falciparum | ||
| 9. | ALA4848632 | 79; DSM705 | EC50 | = | 0.086 | uM | ALA4812778 | 7.07 | nM | Plasmodium falciparum | ||
| 10. | ALA4848632 | 79; DSM705 | EC50 | = | 0.052 | uM | ALA4812777 | 7.28 | nM | Plasmodium falciparum | ||
| 11. | ALA4848632 | 79; DSM705 | EC50 | = | 0.007 | uM | ALA4812776 | 8.16 | nM | Plasmodium falciparum | ||
| 12. | ALA4848632 | 79; DSM705 | EC50 | = | 0.008 | uM | ALA4812775 | 8.12 | nM | Plasmodium falciparum | ||
| 13. | ALA4848632 | 79; DSM705 | EC50 | = | 0.013 | uM | ALA4812774 | 7.89 | nM | Plasmodium berghei | ||
| 14. | ALA4848632 | 79; DSM705 | EC50 | > | 10 | uM | ALA4812773 | nM | Plasmodium falciparum | |||
| 15. | ALA4848632 | 79; DSM705 | EC50 | > | 10 | uM | ALA4812772 | nM | Plasmodium falciparum | |||
| 16. | ALA4848632 | 79; DSM705 | EC50 | = | 0.018 | uM | ALA4812771 | 7.75 | nM | Plasmodium falciparum | ||
| 17. | ALA4848632 | 79; DSM705 | F | = | 77 | % | ALA4812770 | % | ||||
| 18. | ALA4848632 | 79; DSM705 | AUC | = | 47 | uM.hr | ALA4812769 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 19. | ALA4848632 | 79; DSM705 | Cmax | = | 6 | uM | ALA4812768 | nM | ||||
| 20. | ALA4848632 | 79; DSM705 | Tmax | = | 0.7 | hr | ALA4812767 | hr |
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