| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4848754 | 20 | fCmax | = | 1.56 | uM | ALA4810814 | uM | ||||
| 2. | ALA4848754 | 20 | Fu | = | 0.4 | ALA4810813 | ||||||
| 3. | ALA4848754 | 20 | F | = | 71 | % | ALA4810812 | % | ||||
| 4. | ALA4848754 | 20 | F | = | 5 | % | ALA4810811 | % | ||||
| 5. | ALA4848754 | 20 | CL | = | 41 | ml/min.kg | ALA4810810 | mL.min-1.kg-1 | ||||
| 6. | ALA4848754 | 20 | Vdss | = | 0.3 | L/Kg | ALA4810809 | L.kg-1 | ||||
| 7. | ALA4848754 | 20 | t1/2 | = | 0.5 | hr | ALA4810808 | hr | ||||
| 8. | ALA4848754 | 20 | t1/2 | = | 1.3 | hr | ALA4810807 | hr | ||||
| 9. | ALA4848754 | 20 | Ki | = | 0.155 | uM | ALA4810806 | 6.81 | nM | Mus musculus | ||
| 10. | ALA4848754 | 20 | t1/2 | = | 0.2 | hr | ALA4810805 | hr | ||||
| 11. | ALA4848754 | 20 | AUC | = | 1530 | ng/mL.hr | ALA4810804 | ng.hr.mL-1 | ||||
| 12. | ALA4848754 | 20 | AUC | = | 199 | ng/mL.hr | ALA4810803 | ng.hr.mL-1 | ||||
| 13. | ALA4848754 | 20 | AUC | = | 864 | ng/mL.hr | ALA4810802 | ng.hr.mL-1 | ||||
| 14. | ALA4848754 | 20 | Cmax | = | 1550 | ng/ml | ALA4810801 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 15. | ALA4848754 | 20 | Cmax | = | 185 | ng/ml | ALA4810800 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 16. | ALA4848754 | 20 | Tmax | = | 0.25 | hr | ALA4810799 | hr | ||||
| 17. | ALA4848754 | 20 | Tmax | = | 0.08 | hr | ALA4810798 | hr | ||||
| 18. | ALA4848754 | 20 | permeability | = | 5.6 | 10^-6 cm/s | ALA4810797 | 10^-6 cm/s | ||||
| 19. | ALA4848754 | 20 | CLH | = | 23 | microL/min/mg | ALA4810796 | mL.min-1.g-1 | ||||
| 20. | ALA4848754 | 20 | logD | = | 1.8 | ALA4810795 |
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