| # | Name | Compound Key | Action Type | Relation | Activety Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4848885 | 14a | AUC | = | 2356 | hr.ng/ml | ALA4834881 | ng.hr.mL-1 | ||||
| 2. | ALA4848885 | 14a | AUC | = | 555 | hr.ng/ml | ALA4834879 | ng.hr.mL-1 | ||||
| 3. | ALA4848885 | 14a | Cmax | = | 3405 | uM | ALA4834878 | nM | ||||
| 4. | ALA4848885 | 14a | Cmax | = | 785 | uM | ALA4834876 | nM | ||||
| 5. | ALA4848885 | 14a | t1/2 | = | 0.87 | hr | ALA4834875 | hr | ||||
| 6. | ALA4848885 | 14a | t1/2 | = | 0.94 | hr | ALA4834873 | hr | ||||
| 7. | ALA4848885 | 14a | F | = | 44 | % | ALA4834872 | % | ||||
| 8. | ALA4848885 | 14a | F | = | 15.9 | % | ALA4834870 | % | ||||
| 9. | ALA4848885 | 14a | Activity | = | 1967 | ng/ml | ALA4834869 | ng/ml | ||||
| 10. | ALA4848885 | 14a | Activity | = | 2179 | ng/ml | ALA4834866 | ng/ml | ||||
| 11. | ALA4848885 | 14a | t1/2 | = | 0.24 | hr | ALA4834865 | hr | ||||
| 12. | ALA4848885 | 14a | t1/2 | = | 0.25 | hr | ALA4834862 | hr | ||||
| 13. | ALA4848885 | 14a | Vdss | = | 0.49 | L/Kg | ALA4834861 | L.kg-1 | ||||
| 14. | ALA4848885 | 14a | Vdss | = | 58 | L/Kg | ALA4834858 | L.kg-1 | ||||
| 15. | ALA4848885 | 14a | CL | = | 31.2 | ml/min.kg | ALA4834856 | mL.min-1.kg-1 | ||||
| 16. | ALA4848885 | 14a | CL | = | 48.1 | ml/min.kg | ALA4834854 | mL.min-1.kg-1 | ||||
| 17. | ALA4848885 | 14a | EC50 | = | 0.18 | nM | ALA4834853 | 9.74 | nM | Homo sapiens | ||
| 18. | ALA4848885 | 14a | CLH | = | 21.9 | uL/min | ALA4834852 | uL/min | ||||
| 19. | ALA4848885 | 14a | CLH | = | 23.8 | uL/min | ALA4834851 | uL/min | ||||
| 20. | ALA4848885 | 14a | CLH | < | 8.2 | uL/min | ALA4834850 | uL/min |
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