| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4849329 | 9 | permeability | = | 16 | 10^-6 cm/s | ALA4828038 | 10^-6 cm/s | ||||
| 2. | ALA4849329 | 9 | Ratio | = | 7.2 | ALA4828037 | ||||||
| 3. | ALA4849329 | 9 | PPB | = | 80.8 | % | ALA4828036 | % | ||||
| 4. | ALA4849329 | 9 | PPB | = | 85.9 | % | ALA4828035 | % | ||||
| 5. | ALA4849329 | 9 | t1/2 | = | 1.6 | hr | ALA4828034 | hr | ||||
| 6. | ALA4849329 | 9 | fVdss | = | 11 | L/Kg | ALA4828033 | L/Kg | ||||
| 7. | ALA4849329 | 9 | Vdss | = | 2.1 | L/Kg | ALA4828032 | L.kg-1 | ||||
| 8. | ALA4849329 | 9 | CL free | = | 89 | ml/min.Kg | ALA4828031 | mL.min-1.kg-1 | ||||
| 9. | ALA4849329 | 9 | CL | = | 17 | ml/min.Kg | ALA4828030 | mL.min-1.kg-1 | ||||
| 10. | ALA4849329 | 9 | Kinetic_solubility | = | 120 | uM | ALA4828024 | nM | ||||
| 11. | ALA4849329 | 9 | logD | = | 1.8 | ALA4828023 | ||||||
| 12. | ALA4849329 | 9 | fEC50 | = | 53 | nM | ALA4828022 | nM | Rattus norvegicus | |||
| 13. | ALA4849329 | 9 | IC50 | = | 7.4 | nM | ALA4828021 | 8.13 | nM | Rattus norvegicus | ||
| 14. | ALA4849329 | 9 | IC50 | = | 1.2 | nM | ALA4828020 | 8.92 | nM | Homo sapiens | ||
| 15. | ALA4849329 | 9 | IC50 | > | 10 | uM | ALA5055799 | nM | Homo sapiens | |||
| 16. | ALA4849329 | 9 | IC50 | > | 10 | uM | ALA5055798 | nM | Homo sapiens | |||
| 17. | ALA4849329 | 9 | Activity | 0 | ALA5055797 | Dose-dependent effect | Cavia porcellus | |||||
| 18. | ALA4849329 | 9 | IC50 | = | 0.007 | uM | ALA5055796 | 8.15 | nM | |||
| 19. | ALA4849329 | 9 | INH | < | 15 | % | ALA5055795 | % | Homo sapiens | |||
| 20. | ALA4849329 | 9 | INH | < | 15 | % | ALA5055794 | % | Homo sapiens |
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