Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4849497	44	INH	>	90	%	ALA4844619			%	Homo sapiens
2.	ALA4849497	44	INH	>	90	%	ALA4844618			%	Homo sapiens
3.	ALA4849497	44	INH	>	90	%	ALA4844617			%	Homo sapiens
4.	ALA4849497	44	INH	>	90	%	ALA4844616			%	Homo sapiens
5.	ALA4849497	44	IC50	=	11.6	nM	ALA4844615	7.94		nM	Homo sapiens
6.	ALA4849497	44	Emax	=	99	%	ALA4844614			%	Homo sapiens
7.	ALA4849497	44	DC50	=	1.9	nM	ALA4844613			nM	Homo sapiens
8.	ALA4849497	44	IC50	=	4.3	nM	ALA4844612	8.37		nM	Homo sapiens
9.	ALA4849497	44	F	=	34	%	ALA4844606			%
10.	ALA4849497	44	AUCt	=	1134	hr.ng/ml	ALA4844605			ng.hr.mL-1
11.	ALA4849497	44	Cmax	=	92.2	ng/ml	ALA4844604		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
12.	ALA4849497	44	t1/2	=	8.1	hr	ALA4844603			hr
13.	ALA4849497	44	Tmax	=	4	hr	ALA4844602			hr
14.	ALA4849497	44	Vdss	=	8.3	L/Kg	ALA4844598			L.kg-1
15.	ALA4849497	44	AUCt	=	1118	hr.ng/ml	ALA4844597			ng.hr.mL-1
16.	ALA4849497	44	t1/2	=	8.8	hr	ALA4844596			hr
17.	ALA4849497	44	Emax	=	100	%	ALA4844595			%	Homo sapiens
18.	ALA4849497	44	DC50	=	0.1	uM	ALA4844594			uM	Homo sapiens