# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4849710 | 49b | solubility | < | 1 | ug ml-1 | ALA4835965 | ug.mL-1 | ||||
2. | ALA4849710 | 49b | permeability | = | 257 | nm/s | ALA4835964 | nm/s | ||||
3. | ALA4849710 | 49b | permeability | < | 15 | nm/s | ALA4835963 | nm/s | ||||
4. | ALA4849710 | 49b | permeability | = | 87 | nm/s | ALA4835962 | nm/s | ||||
5. | ALA4849710 | 49b | permeability | = | 99 | nm/s | ALA4835961 | nm/s | ||||
6. | ALA4849710 | 49b | Fu | = | 5.4 | % | ALA4835959 | |||||
7. | ALA4849710 | 49b | Cp | = | 140 | nM | ALA4835956 | nM | ||||
8. | ALA4849710 | 49b | Activity | = | 56 | % | ALA4835953 | % | Callithrix jacchus | |||
9. | ALA4849710 | 49b | Activity | = | 48 | % | ALA4835952 | % | Callithrix jacchus | |||
10. | ALA4849710 | 49b | Activity | = | 47 | % | ALA4835951 | % | Callithrix jacchus | |||
11. | ALA4849710 | 49b | IC50 | > | 40 | uM | ALA4835950 | nM | Homo sapiens | |||
12. | ALA4849710 | 49b | Cmax | = | 4 | nM | ALA4835948 | nM | ||||
13. | ALA4849710 | 49b | Stabilty | = | 28 | % | ALA4835947 | % | ||||
14. | ALA4849710 | 49b | Stabilty | = | 82 | % | ALA4835946 | % | ||||
15. | ALA4849710 | 49b | Stabilty | = | 91 | % | ALA4835945 | % | ||||
16. | ALA4849710 | 49b | Ki | = | 0.13 | nM | ALA4835944 | 9.89 | nM | Homo sapiens |