# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4852166 | 6f | t1/2 | = | 10.2 | hr | ALA4836892 | hr | ||||
2. | ALA4852166 | 6f | Tmax | = | 0.5 | hr | ALA4836891 | hr | ||||
3. | ALA4852166 | 6f | Cmax | = | 18.34 | ng/ml | ALA4836890 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4852166 | 6f | AUClast | = | 81.04 | hr.ng/ml | ALA4836889 | ng.hr.mL-1 | ||||
5. | ALA4852166 | 6f | INH | 0 | ALA4836886 | Active | % | Homo sapiens | ||||
6. | ALA4852166 | 6f | INH | 0 | ALA4836885 | Active | % | Homo sapiens | ||||
7. | ALA4852166 | 6f | IC50 | > | 100 | uM | ALA4836884 | nM | Homo sapiens | |||
8. | ALA4852166 | 6f | INH | = | 3.93 | % | ALA4836883 | % | Homo sapiens | |||
9. | ALA4852166 | 6f | t1/2 | = | 7.7 | hr | ALA4836882 | hr | ||||
10. | ALA4852166 | 6f | Tmax | = | 1 | hr | ALA4836881 | hr | ||||
11. | ALA4852166 | 6f | Cmax | = | 41.89 | ng/ml | ALA4836880 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
12. | ALA4852166 | 6f | AUClast | = | 255 | hr.ng/ml | ALA4836879 | ng.hr.mL-1 | ||||
13. | ALA4852166 | 6f | Activity | 0 | ALA4836878 | Non-Toxic | ||||||
14. | ALA4852166 | 6f | TGI | = | 55.1 | % | ALA4836877 | % | Homo sapiens | |||
15. | ALA4852166 | 6f | Activity | = | 2.47 | % | ALA4836876 | % | Homo sapiens | |||
16. | ALA4852166 | 6f | Activity | = | 30.3 | % | ALA4836875 | % | Homo sapiens | |||
17. | ALA4852166 | 6f | Activity | = | 17.8 | % | ALA4836874 | % | Homo sapiens | |||
18. | ALA4852166 | 6f | Activity | = | 49.5 | % | ALA4836873 | % | Homo sapiens | |||
19. | ALA4852166 | 6f | Activity | = | 1.77 | % | ALA4836872 | % | Homo sapiens | |||
20. | ALA4852166 | 6f | Activity | = | 24.2 | % | ALA4836871 | % | Homo sapiens |