# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4852189 | 1b | Papp | = | 220 | nm/s | ALA4836341 | nm/s | ||||
2. | ALA4852189 | 1b | Cmax | = | 350 | ng/ml | ALA4836340 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
3. | ALA4852189 | 1b | beta t1/2 | = | 2.2 | hr | ALA4836339 | hr | ||||
4. | ALA4852189 | 1b | AUC/dose | = | 426 | ng.hr/ml | ALA4836338 | ng.hr/ml | ||||
5. | ALA4852189 | 1b | solubility | = | 0.004 | mg/ml | ALA4836337 | ug.mL-1 | ||||
6. | ALA4852189 | 1b | IC50 | = | 45 | nM | ALA4836336 | 7.35 | nM | Homo sapiens | ||
7. | ALA4852189 | 1b | t1/2 | > | 180 | min | ALA4836335 | hr | ||||
8. | ALA4852189 | 1b | IC50 | = | 510 | nM | ALA4836334 | 6.29 | nM | Rattus norvegicus |