| # | Name | Compound Key | Action Type | Relation | Activety Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4852440 | 19b | AUC | = | 1388 | hr.ng/ml | ALA4834881 | ng.hr.mL-1 | ||||
| 2. | ALA4852440 | 19b | Cmax | = | 1575 | uM | ALA4834878 | nM | ||||
| 3. | ALA4852440 | 19b | t1/2 | = | 0.73 | hr | ALA4834875 | hr | ||||
| 4. | ALA4852440 | 19b | F | = | 64.4 | % | ALA4834872 | % | ||||
| 5. | ALA4852440 | 19b | Activity | = | 683 | ng/ml | ALA4834869 | ng/ml | ||||
| 6. | ALA4852440 | 19b | t1/2 | = | 0.29 | hr | ALA4834865 | hr | ||||
| 7. | ALA4852440 | 19b | Vdss | = | 1.45 | L/Kg | ALA4834861 | L.kg-1 | ||||
| 8. | ALA4852440 | 19b | CL | = | 77.5 | ml/min.kg | ALA4834856 | mL.min-1.kg-1 | ||||
| 9. | ALA4852440 | 19b | EC50 | = | 0.32 | nM | ALA4834853 | 9.49 | nM | Homo sapiens | ||
| 10. | ALA4852440 | 19b | CLH | = | 20.7 | uL/min | ALA4834852 | uL/min | ||||
| 11. | ALA4852440 | 19b | CLH | = | 10.1 | uL/min | ALA4834851 | uL/min | ||||
| 12. | ALA4852440 | 19b | CLH | < | 8.2 | uL/min | ALA4834850 | uL/min | ||||
| 13. | ALA4852440 | 19b | t1/2 | = | 74.9 | min | ALA4834849 | hr | ||||
| 14. | ALA4852440 | 19b | t1/2 | = | 98.1 | min | ALA4834848 | hr | ||||
| 15. | ALA4852440 | 19b | t1/2 | > | 120 | min | ALA4834847 | hr | ||||
| 16. | ALA4852440 | 19b | Kinetic_solubility | = | 197.9 | uM | ALA4834846 | nM | ||||
| 17. | ALA4852440 | 19b | Papp | = | 39.9 | 10^-6 cm/s | ALA4834845 | 10^-6 cm/s | ||||
| 18. | ALA4852440 | 19b | Papp | = | 15.8 | 10^-6 cm/s | ALA4834844 | 10^-6 cm/s | ||||
| 19. | ALA4852440 | 19b | pKa | 0 | ALA4834843 | Not Determined | ||||||
| 20. | ALA4852440 | 19b | logD | = | 1.27 | ALA4834842 |
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