# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4854482 | 61 | F | = | 1.54 | % | ALA4824124 | % | ||||
2. | ALA4854482 | 61 | AUClast | = | 94.3 | ug.hr/ml | ALA4824123 | ng.hr.mL-1 | ||||
3. | ALA4854482 | 61 | Clast | = | 2.76 | ng/ml | ALA4824122 | ng/ml | ||||
4. | ALA4854482 | 61 | AUClast | = | 541 | ug.hr/ml | ALA4824121 | ng.hr.mL-1 | ||||
5. | ALA4854482 | 61 | t1/2 | = | 0.81 | hr | ALA4824120 | hr | ||||
6. | ALA4854482 | 61 | Vdss | = | 1.12 | L/Kg | ALA4824119 | L.kg-1 | ||||
7. | ALA4854482 | 61 | Clast | = | 2.99 | ng/ml | ALA4824118 | ng/ml | ||||
8. | ALA4854482 | 61 | CL | = | 31.2 | ml/min.kg | ALA4824117 | mL.min-1.kg-1 | ||||
9. | ALA4854482 | 61 | Fu | < | 1 | ALA4824116 | ||||||
10. | ALA4854482 | 61 | Fu | < | 1 | ALA4824112 | ||||||
11. | ALA4854482 | 61 | pEC50 | < | 4.2 | ALA4824111 | nM | Homo sapiens | ||||
12. | ALA4854482 | 61 | solubility | = | 511 | uM | ALA4824110 | nM | ||||
13. | ALA4854482 | 61 | CLH | = | 164 | uL/min | ALA4824109 | uL/min | ||||
14. | ALA4854482 | 61 | CLH | = | 146 | uL/min | ALA4824108 | uL/min | ||||
15. | ALA4854482 | 61 | pEC50 | = | 7.36 | ALA4824107 | 7.36 | nM | Mus musculus | |||
16. | ALA4854482 | 61 | pEC50 | = | 7.36 | ALA4824105 | 7.36 | nM | Homo sapiens | |||
17. | ALA4854482 | 61 | Papp | = | 106.8 | nm/s | ALA4824104 | nm/s | ||||
18. | ALA4854482 | 61 | Ratio | = | 1.08 | ALA4824103 | ||||||
19. | ALA4854482 | 61 | pEC50 | < | 4.8 | ALA4824102 | nM | Homo sapiens | ||||
20. | ALA4854482 | 61 | pEC50 | < | 4.8 | ALA4824101 | nM | Homo sapiens |