Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activety Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4854836	14b	AUC	=	6336	hr.ng/ml	ALA4834881		ng.hr.mL-1
2.	ALA4854836	14b	AUC	=	2454	hr.ng/ml	ALA4834879		ng.hr.mL-1
3.	ALA4854836	14b	Cmax	=	5010	uM	ALA4834878		nM
4.	ALA4854836	14b	Cmax	=	1610	uM	ALA4834876		nM
5.	ALA4854836	14b	t1/2	=	1.58	hr	ALA4834875		hr
6.	ALA4854836	14b	t1/2	=	1.14	hr	ALA4834873		hr
7.	ALA4854836	14b	F	=	71.3	%	ALA4834872		%
8.	ALA4854836	14b	F	=	36.5	%	ALA4834870		%
9.	ALA4854836	14b	Activity	=	1956	ng/ml	ALA4834869		ng/ml
10.	ALA4854836	14b	Activity	=	1544	ng/ml	ALA4834866		ng/ml
11.	ALA4854836	14b	t1/2	=	30	hr	ALA4834865		hr
12.	ALA4854836	14b	t1/2	=	0.52	hr	ALA4834862		hr
13.	ALA4854836	14b	Vdss	=	0.45	L/Kg	ALA4834861		L.kg-1
14.	ALA4854836	14b	Vdss	=	0.65	L/Kg	ALA4834858		L.kg-1
15.	ALA4854836	14b	CL	=	18.8	ml/min.kg	ALA4834856		mL.min-1.kg-1
16.	ALA4854836	14b	CL	=	26	ml/min.kg	ALA4834854		mL.min-1.kg-1
17.	ALA4854836	14b	EC50	=	1.92	nM	ALA4834853	8.72	nM	Homo sapiens
18.	ALA4854836	14b	CLH	=	11.9	uL/min	ALA4834852		uL/min
19.	ALA4854836	14b	CLH	<	8.2	uL/min	ALA4834851		uL/min
20.	ALA4854836	14b	CLH	<	8.2	uL/min	ALA4834850		uL/min