# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4856292 | Larotrectinib | IC50 | > | 100 | uM | ALA5139873 | nM | Homo sapiens | |||
2. | ALA4856292 | Larotrectinib | TGI | = | 78 | % | ALA5139869 | % | Homo sapiens | |||
3. | ALA4856292 | Larotrectinib | Activity | 0 | ALA5139867 | Non-Toxic | ||||||
4. | ALA4856292 | Larotrectinib | IC50 | = | 0.26 | uM | ALA5139776 | 6.58 | nM | Mus musculus | ||
5. | ALA4856292 | Larotrectinib | IC50 | = | 0.85 | uM | ALA5139775 | 6.07 | nM | Mus musculus | ||
6. | ALA4856292 | Larotrectinib | IC50 | = | 2.2 | uM | ALA5139774 | 5.66 | nM | Mus musculus | ||
7. | ALA4856292 | Larotrectinib | IC50 | > | 100 | uM | ALA5139773 | nM | Homo sapiens | |||
8. | ALA4856292 | Larotrectinib | IC50 | > | 100 | uM | ALA5139772 | nM | Homo sapiens | |||
9. | ALA4856292 | Larotrectinib | IC50 | = | 0.007 | uM | ALA5139771 | 8.15 | nM | Homo sapiens | ||
10. | ALA4856292 | Larotrectinib | IC50 | = | 0.003 | uM | ALA5139765 | 8.57 | nM | Homo sapiens | ||
11. | ALA4856292 | Larotrectinib | IC50 | = | 0.003 | uM | ALA5139764 | 8.54 | nM | Homo sapiens | ||
12. | ALA4856292 | Larotrectinib | IC50 | = | 0.004 | uM | ALA5139763 | 8.39 | nM | Homo sapiens | ||
13. | ALA4856292 | Larotrectinib | IC50 | = | 0.001 | uM | ALA4840466 | 9.00 | nM | Homo sapiens | ||
14. | ALA4856292 | Larotrectinib | IC50 | = | 0.005 | uM | ALA4840465 | 8.33 | nM | Homo sapiens | ||
15. | ALA4856292 | Larotrectinib | IC50 | = | 0.003 | uM | ALA4840464 | 8.47 | nM | Homo sapiens | ||
16. | ALA4856292 | Larotrectinib | IC50 | = | 3.9 | nM | ALA5053804 | 8.41 | nM | Homo sapiens | ||
17. | ALA4856292 | Larotrectinib | Ratio IC50 | = | 0.004 | ALA5053803 | ||||||
18. | ALA4856292 | Larotrectinib | Ratio IC50 | = | 0.004 | ALA5053802 | ||||||
19. | ALA4856292 | Larotrectinib | Ratio IC50 | = | 0.002 | ALA5053801 | ||||||
20. | ALA4856292 | Larotrectinib | IC50 | = | 20.7 | nM | ALA5053800 | 7.68 | nM |