# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4856710 | 71 | IC90 | = | 228 | nM | ALA4843309 | nM | Mus musculus | |||
2. | ALA4856710 | 71 | IC50 | = | 25 | nM | ALA4843309 | 7.60 | nM | Mus musculus | ||
3. | ALA4856710 | 71 | IC50 | = | 14 | nM | ALA4843307 | 7.85 | nM | Homo sapiens | ||
4. | ALA4856710 | 71 | IC90 | = | 124 | nM | ALA4843307 | nM | Homo sapiens | |||
5. | ALA4856710 | 71 | INH | = | 9 | % | ALA4843306 | % | Mus musculus | |||
6. | ALA4856710 | 71 | INH | = | 33 | % | ALA4843305 | % | Mus musculus | |||
7. | ALA4856710 | 71 | PPB | = | 99.01 | % | ALA4843301 | % | ||||
8. | ALA4856710 | 71 | Cp | = | 0.01 | uM | ALA4843300 | uM | ||||
9. | ALA4856710 | 71 | Cp | = | 0.06 | uM | ALA4843299 | uM | ||||
10. | ALA4856710 | 71 | Drug uptake | = | 0.7 | uM | ALA4843295 | uM | ||||
11. | ALA4856710 | 71 | Drug uptake | = | 0.5 | uM | ALA4843294 | uM | ||||
12. | ALA4856710 | 71 | IC50 | = | 6.2 | uM | ALA4843280 | 5.21 | nM | Homo sapiens | ||
13. | ALA4856710 | 71 | PPB | = | 99 | % | ALA4843276 | % | ||||
14. | ALA4856710 | 71 | Ratio IC50 | > | 5000 | ALA4843254 | ||||||
15. | ALA4856710 | 71 | IC50 | > | 3 | uM | ALA4843253 | nM | Homo sapiens | |||
16. | ALA4856710 | 71 | IC50 | > | 44 | uM | ALA4843250 | nM | Homo sapiens | |||
17. | ALA4856710 | 71 | F | = | 48 | % | ALA4843249 | % | ||||
18. | ALA4856710 | 71 | Cmax | = | 5.2 | uM | ALA4843248 | nM | ||||
19. | ALA4856710 | 71 | AUC | = | 3.3 | uM.hr | ALA4843247 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
20. | ALA4856710 | 71 | beta t1/2 | = | 5.3 | hr | ALA4843246 | hr |