# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4857098 | 40 | t1/2 | = | 0.7 | hr | ALA4809948 | hr | ||||
2. | ALA4857098 | 40 | CL free | = | 95 | ml/min.kg | ALA4809946 | mL.min-1.kg-1 | ||||
3. | ALA4857098 | 40 | Fu | = | 0.401 | ALA4809922 | ||||||
4. | ALA4857098 | 40 | F | = | 77 | % | ALA4809920 | % | ||||
5. | ALA4857098 | 40 | Vdss | = | 1.8 | L/Kg | ALA4809918 | L.kg-1 | ||||
6. | ALA4857098 | 40 | CL | = | 57 | ml/min.kg | ALA4809916 | mL.min-1.kg-1 | ||||
7. | ALA4857098 | 40 | CLH | < | 0.45 | ml/min/g | ALA4809915 | mL.min-1.g-1 | ||||
8. | ALA4857098 | 40 | CLH | < | 0.65 | ml/min/g | ALA4809914 | mL.min-1.g-1 | ||||
9. | ALA4857098 | 40 | CLH | < | 0.8 | ml/min/g | ALA4809913 | mL.min-1.g-1 | ||||
10. | ALA4857098 | 40 | pIC50 | = | 6.5 | ALA4809912 | 6.50 | nM | Homo sapiens | |||
11. | ALA4857098 | 40 | permeability | = | 56 | nm/s | ALA4809911 | nm/s | ||||
12. | ALA4857098 | 40 | solubility | = | 962 | ug ml-1 | ALA4809910 | ug.mL-1 | ||||
13. | ALA4857098 | 40 | logD | = | 2.9 | ALA4809909 | ||||||
14. | ALA4857098 | 40 | Selectivity Index | = | 1250 | ALA4809908 | ||||||
15. | ALA4857098 | 40 | pIC50 | = | 7.6 | ALA4809907 | 7.60 | nM | Homo sapiens | |||
16. | ALA4857098 | 40 | pIC50 | = | 4.5 | ALA4809906 | 4.50 | nM | Homo sapiens |