# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4857273 | 10a | Activity | > | 20 | uM | ALA4834385 | uM | ||||
2. | ALA4857273 | 10a | Activity | > | 20 | uM | ALA4834384 | uM | ||||
3. | ALA4857273 | 10a | IC50 | > | 20 | uM | ALA4834383 | nM | Plasmodium cynomolgi | |||
4. | ALA4857273 | 10a | IC50 | = | 11.59 | uM | ALA4834382 | 4.94 | nM | Plasmodium cynomolgi | ||
5. | ALA4857273 | 10a | IC50 | > | 20 | uM | ALA4834381 | nM | Plasmodium cynomolgi | |||
6. | ALA4857273 | 10a | IC50 | = | 7.91 | uM | ALA4834380 | 5.10 | nM | Plasmodium cynomolgi | ||
7. | ALA4857273 | 10a | INH | = | 89 | % | ALA4834377 | % | Plasmodium berghei | |||
8. | ALA4857273 | 10a | INH | = | 78 | % | ALA4834376 | % | Plasmodium berghei | |||
9. | ALA4857273 | 10a | Kinetic_solubility | = | 200 | uM | ALA4834372 | nM | ||||
10. | ALA4857273 | 10a | t1/2 | < | 2 | min | ALA4834371 | hr | ||||
11. | ALA4857273 | 10a | t1/2 | < | 2 | min | ALA4834370 | hr | ||||
12. | ALA4857273 | 10a | INH | = | 3 | % | ALA4834369 | % | Plasmodium falciparum | |||
13. | ALA4857273 | 10a | INH | = | 3 | % | ALA4834368 | % | ||||
14. | ALA4857273 | 10a | IC50 | = | 320 | nM | ALA4834366 | 6.50 | nM | |||
15. | ALA4857273 | 10a | IC50 | = | 0.94 | uM | ALA4834365 | 6.03 | nM | Homo sapiens |