# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4857649 | 25c | solubility | < | 1 | ug ml-1 | ALA4835965 | ug.mL-1 | ||||
2. | ALA4857649 | 25c | permeability | = | 24 | nm/s | ALA4835964 | nm/s | ||||
3. | ALA4857649 | 25c | permeability | < | 15 | nm/s | ALA4835963 | nm/s | ||||
4. | ALA4857649 | 25c | permeability | 0 | ALA4835962 | Not Determined | ||||||
5. | ALA4857649 | 25c | permeability | = | 513 | nm/s | ALA4835961 | nm/s | ||||
6. | ALA4857649 | 25c | Cmax | = | 87 | nM | ALA4835960 | nM | ||||
7. | ALA4857649 | 25c | Fu | = | 0.9 | % | ALA4835959 | |||||
8. | ALA4857649 | 25c | Cp | = | 80 | nM | ALA4835956 | nM | ||||
9. | ALA4857649 | 25c | Activity | = | 84 | % | ALA4835953 | % | Callithrix jacchus | |||
10. | ALA4857649 | 25c | Activity | = | 65 | % | ALA4835952 | % | Callithrix jacchus | |||
11. | ALA4857649 | 25c | Activity | = | 26 | % | ALA4835951 | % | Callithrix jacchus | |||
12. | ALA4857649 | 25c | IC50 | = | 8.4 | uM | ALA4835950 | 5.08 | nM | Homo sapiens | ||
13. | ALA4857649 | 25c | IC50 | = | 0.12 | nM | ALA4835949 | 9.92 | nM | Homo sapiens | ||
14. | ALA4857649 | 25c | Cmax | = | 270 | nM | ALA4835948 | nM | ||||
15. | ALA4857649 | 25c | Stabilty | = | 87 | % | ALA4835947 | % | ||||
16. | ALA4857649 | 25c | Stabilty | = | 54 | % | ALA4835946 | % | ||||
17. | ALA4857649 | 25c | Stabilty | = | 58 | % | ALA4835945 | % | ||||
18. | ALA4857649 | 25c | Ki | = | 0.02 | nM | ALA4835944 | 10.70 | nM | Homo sapiens |