| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4858566 | 24f | IC50 | = | 0.2 | ug ml-1 | ALA4831718 | ug.mL-1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
| 2. | ALA4858566 | 24f | Ratio | > | 8 | ALA4831717 | ||||||
| 3. | ALA4858566 | 24f | MIC | = | 0.064 | ug ml-1 | ALA4831716 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 4. | ALA4858566 | 24f | MIC | = | 0.13 | ug ml-1 | ALA4831715 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 5. | ALA4858566 | 24f | MIC | > | 0.51 | ug ml-1 | ALA4831714 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 6. | ALA4858566 | 24f | CL | = | 479 | ml/min.kg | ALA4831709 | mL.min-1.kg-1 | ||||
| 7. | ALA4858566 | 24f | MRT | = | 0.13 | hr | ALA4831708 | hr | ||||
| 8. | ALA4858566 | 24f | AUC | = | 184 | ng.hr/ml | ALA4831707 | ng.hr.mL-1 | ||||
| 9. | ALA4858566 | 24f | AUCt | = | 183 | ng.hr/ml | ALA4831706 | ng.hr.mL-1 | ||||
| 10. | ALA4858566 | 24f | Cmax | = | 1299 | ng/ml | ALA4831705 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA4858566 | 24f | beta t1/2 | = | 0.13 | hr | ALA4831704 | hr | ||||
| 12. | ALA4858566 | 24f | F | = | 2.3 | % | ALA4831703 | % | ||||
| 13. | ALA4858566 | 24f | MRT | = | 2.1 | hr | ALA4831702 | hr | ||||
| 14. | ALA4858566 | 24f | AUC | = | 57.9 | ng.hr/ml | ALA4831701 | ng.hr.mL-1 | ||||
| 15. | ALA4858566 | 24f | AUCt | = | 41.9 | ng.hr/ml | ALA4831700 | ng.hr.mL-1 | ||||
| 16. | ALA4858566 | 24f | Cmax | = | 25.4 | ng/ml | ALA4831699 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA4858566 | 24f | Tmax | = | 1 | hr | ALA4831698 | hr | ||||
| 18. | ALA4858566 | 24f | beta t1/2 | = | 1.7 | hr | ALA4831697 | hr | ||||
| 19. | ALA4858566 | 24f | IC50 | > | 30 | ug ml-1 | ALA4831696 | ug.mL-1 | Homo sapiens | |||
| 20. | ALA4858566 | 24f | IC50 | > | 64 | ug ml-1 | ALA4831695 | ug.mL-1 | Homo sapiens |
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