# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4859691 | 49 | Activity | = | 44.9 | % | ALA4830304 | % | ||||
2. | ALA4859691 | 49 | Activity | = | 50.24 | % | ALA4830303 | % | Homo sapiens | |||
3. | ALA4859691 | 49 | F | = | 20.6 | % | ALA4830302 | % | ||||
4. | ALA4859691 | 49 | AUC | = | 4434 | ng/mL.hr | ALA4830301 | ng.hr.mL-1 | ||||
5. | ALA4859691 | 49 | AUClast | = | 4190 | ng/mL.hr | ALA4830300 | ng.hr.mL-1 | ||||
6. | ALA4859691 | 49 | t1/2 | = | 0.824 | hr | ALA4830299 | hr | ||||
7. | ALA4859691 | 49 | Cmax | = | 1110 | ng/ml | ALA4830298 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA4859691 | 49 | Tmax | = | 1.667 | hr | ALA4830297 | hr | ||||
9. | ALA4859691 | 49 | MRT | = | 0.704 | hr | ALA4830296 | hr | ||||
10. | ALA4859691 | 49 | AUC | = | 10209 | ng/mL.hr | ALA4830295 | ng.hr.mL-1 | ||||
11. | ALA4859691 | 49 | AUClast | = | 10203 | ng/mL.hr | ALA4830294 | ng.hr.mL-1 | ||||
12. | ALA4859691 | 49 | t1/2 | = | 0.773 | hr | ALA4830293 | hr | ||||
13. | ALA4859691 | 49 | Vdss | = | 0.346 | L/Kg | ALA4830292 | L.kg-1 | ||||
14. | ALA4859691 | 49 | CL | = | 0.492 | L/Kg.hr | ALA4830291 | L/Kg.hr | ||||
15. | ALA4859691 | 49 | IC50 | = | 0.05 | uM | ALA4830290 | 7.30 | nM | Homo sapiens | ||
16. | ALA4859691 | 49 | IC50 | = | 0.06 | uM | ALA4830289 | 7.22 | nM | Homo sapiens | ||
17. | ALA4859691 | 49 | IC50 | = | 0.42 | uM | ALA4830288 | 6.38 | nM | Homo sapiens | ||
18. | ALA4859691 | 49 | IC50 | = | 0.33 | uM | ALA4830287 | 6.48 | nM | Homo sapiens | ||
19. | ALA4859691 | 49 | IC50 | = | 0.96 | uM | ALA4830286 | 6.02 | nM | Homo sapiens | ||
20. | ALA4859691 | 49 | IC50 | = | 0.38 | uM | ALA4830285 | 6.42 | nM | Homo sapiens |