# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4859812 | 55 | IC50 | > | 100 | uM | ALA4835259 | nM | Homo sapiens | |||
2. | ALA4859812 | 55 | IC50 | > | 100 | uM | ALA4835258 | nM | Homo sapiens | |||
3. | ALA4859812 | 55 | CLH | < | 1.49 | L/hr.Kg | ALA4835257 | mL.min-1.kg-1 | ||||
4. | ALA4859812 | 55 | CL | < | 1.95 | L/hr.Kg | ALA4835254 | mL.min-1.kg-1 | ||||
5. | ALA4859812 | 55 | Papp | = | 6.1 | 10^-6 cm/s | ALA4835226 | 10^-6 cm/s | ||||
6. | ALA4859812 | 55 | INH | = | 50 | % | ALA4835211 | % | Mus musculus | |||
7. | ALA4859812 | 55 | INH | = | 31 | % | ALA4835210 | % | Mus musculus | |||
8. | ALA4859812 | 55 | PPB | = | 82 | % | ALA4835209 | % | ||||
9. | ALA4859812 | 55 | Cmax | = | 849 | ng/ml | ALA4835205 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA4859812 | 55 | AUC | = | 5814 | ng.hr/ml | ALA4835204 | ng.hr.mL-1 | ||||
11. | ALA4859812 | 55 | INH | 0 | ALA4835203 | Not Active | % | Homo sapiens | ||||
12. | ALA4859812 | 55 | PPB | = | 87 | % | ALA4835199 | % | ||||
13. | ALA4859812 | 55 | INH | < | 50 | % | ALA4835198 | % | Homo sapiens | |||
14. | ALA4859812 | 55 | INH | < | 50 | % | ALA4835197 | % | Homo sapiens | |||
15. | ALA4859812 | 55 | INH | < | 50 | % | ALA4835196 | % | Homo sapiens | |||
16. | ALA4859812 | 55 | INH | < | 50 | % | ALA4835195 | % | Homo sapiens | |||
17. | ALA4859812 | 55 | INH | < | 50 | % | ALA4835194 | % | Homo sapiens | |||
18. | ALA4859812 | 55 | INH | < | 50 | % | ALA4835193 | % | Homo sapiens | |||
19. | ALA4859812 | 55 | CLH | = | 2.64 | L/hr/kg | ALA4835192 | mL.min-1.kg-1 | ||||
20. | ALA4859812 | 55 | CLH | = | 1.41 | L/hr/kg | ALA4835191 | mL.min-1.kg-1 |