# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4859922 | 20i | Cmax | = | 430 | ng/ml | ALA4836340 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
2. | ALA4859922 | 20i | beta t1/2 | = | 0.5 | hr | ALA4836339 | hr | ||||
3. | ALA4859922 | 20i | AUC/dose | = | 125 | ng.hr/ml | ALA4836338 | ng.hr/ml | ||||
4. | ALA4859922 | 20i | solubility | = | 0.002 | mg/ml | ALA4836337 | ug.mL-1 | ||||
5. | ALA4859922 | 20i | IC50 | = | 12 | nM | ALA4836336 | 7.92 | nM | Homo sapiens | ||
6. | ALA4859922 | 20i | t1/2 | > | 180 | min | ALA4836335 | hr | ||||
7. | ALA4859922 | 20i | IC50 | = | 190 | nM | ALA4836334 | 6.72 | nM | Rattus norvegicus |