# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4860329 | 28 | Activity | 0 | ALA4834050 | Non-Toxic | ||||||
2. | ALA4860329 | 28 | Activity | = | 98 | % | ALA4834049 | % | Homo sapiens | |||
3. | ALA4860329 | 28 | Activity | = | 82 | % | ALA4834048 | % | Homo sapiens | |||
4. | ALA4860329 | 28 | IC50 | = | 9 | uM | ALA4834047 | 5.05 | nM | Homo sapiens | ||
5. | ALA4860329 | 28 | Therm_solubility | = | 47 | uM | ALA4834044 | nM | ||||
6. | ALA4860329 | 28 | CLH | < | 1 | uL/min | ALA4834043 | uL/min | ||||
7. | ALA4860329 | 28 | F | = | 67 | % | ALA4834042 | % | ||||
8. | ALA4860329 | 28 | Vdss | = | 3 | L/Kg | ALA4834041 | L.kg-1 | ||||
9. | ALA4860329 | 28 | CL | = | 29 | ml/min.kg | ALA4834040 | mL.min-1.kg-1 | ||||
10. | ALA4860329 | 28 | pIC50 | = | 7.6 | ALA4834039 | 7.60 | nM | Homo sapiens | |||
11. | ALA4860329 | 28 | GI50 | = | 27 | nM | ALA4834039 | nM | Homo sapiens | |||
12. | ALA4860329 | 28 | solubility | = | 130 | uM | ALA4834038 | nM | ||||
13. | ALA4860329 | 28 | CLH | = | 11 | microL/min/mg | ALA4834037 | mL.min-1.g-1 | ||||
14. | ALA4860329 | 28 | logD | = | 1.8 | ALA4834036 | ||||||
15. | ALA4860329 | 28 | pIC50 | = | 7.4 | ALA4834035 | 7.40 | nM | Homo sapiens | |||
16. | ALA4860329 | 28 | IC50 | = | 0.044 | uM | ALA4834035 | 7.36 | nM | Homo sapiens |