# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4861625 | 72 | F | = | 45 | % | ALA4808448 | % | ||||
2. | ALA4861625 | 72 | MRT | = | 9.9 | hr | ALA4808447 | hr | ||||
3. | ALA4861625 | 72 | Vdu | = | 43 | L/Kg | ALA4808446 | L.kg-1 | ||||
4. | ALA4861625 | 72 | CL free | = | 72 | ml/min.kg | ALA4808445 | mL.min-1.kg-1 | ||||
5. | ALA4861625 | 72 | logD | = | 130 | ALA4808444 | ||||||
6. | ALA4861625 | 72 | solubility | = | 25 | uM | ALA4808443 | nM | ||||
7. | ALA4861625 | 72 | solubility | = | 190 | uM | ALA4808442 | nM | ||||
8. | ALA4861625 | 72 | F | = | 24 | % | ALA4808441 | % | ||||
9. | ALA4861625 | 72 | MRT | = | 2.5 | hr | ALA4808440 | hr | ||||
10. | ALA4861625 | 72 | Vdu | = | 54 | L/Kg | ALA4808439 | L.kg-1 | ||||
11. | ALA4861625 | 72 | CL free | = | 368 | ml/min.kg | ALA4808438 | mL.min-1.kg-1 | ||||
12. | ALA4861625 | 72 | CL | = | 14 | ml/min.kg | ALA4808437 | mL.min-1.kg-1 | ||||
13. | ALA4861625 | 72 | EC50 | = | 5.8 | nM | ALA4808436 | 8.24 | nM | Homo sapiens | ||
14. | ALA4861625 | 72 | EC50 | = | 0.84 | nM | ALA4808435 | 9.08 | nM | Homo sapiens |