# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4862372 | 36; GSK097 | Kd | = | 3100 | nM | ALA4809950 | 5.51 | nM | Homo sapiens | ||
2. | ALA4862372 | 36; GSK097 | t1/2 | = | 0.6 | hr | ALA4809949 | hr | ||||
3. | ALA4862372 | 36; GSK097 | t1/2 | = | 2 | hr | ALA4809948 | hr | ||||
4. | ALA4862372 | 36; GSK097 | CL free | = | 102 | ml/min.kg | ALA4809947 | mL.min-1.kg-1 | ||||
5. | ALA4862372 | 36; GSK097 | CL free | = | 96 | ml/min.kg | ALA4809946 | mL.min-1.kg-1 | ||||
6. | ALA4862372 | 36; GSK097 | Selectivity Index | = | 13000 | ALA4809945 | ||||||
7. | ALA4862372 | 36; GSK097 | pKd | = | 8.7 | ALA4809944 | 8.70 | nM | Homo sapiens | |||
8. | ALA4862372 | 36; GSK097 | pKd | = | 4.6 | ALA4809943 | 4.60 | nM | Homo sapiens | |||
9. | ALA4862372 | 36; GSK097 | Selectivity Index | = | 6300 | ALA4809942 | ||||||
10. | ALA4862372 | 36; GSK097 | pKd | = | 8.9 | ALA4809941 | 8.90 | nM | Homo sapiens | |||
11. | ALA4862372 | 36; GSK097 | pKd | = | 5.1 | ALA4809940 | 5.10 | nM | Homo sapiens | |||
12. | ALA4862372 | 36; GSK097 | Selectivity Index | = | 1300 | ALA4809939 | ||||||
13. | ALA4862372 | 36; GSK097 | pKd | = | 8.3 | ALA4809938 | 8.30 | nM | Homo sapiens | |||
14. | ALA4862372 | 36; GSK097 | pKd | = | 5.2 | ALA4809937 | 5.20 | nM | Homo sapiens | |||
15. | ALA4862372 | 36; GSK097 | Selectivity Index | = | 2500 | ALA4809936 | ||||||
16. | ALA4862372 | 36; GSK097 | pKd | = | 8 | ALA4809935 | 8.00 | nM | Homo sapiens | |||
17. | ALA4862372 | 36; GSK097 | pKd | = | 4.6 | ALA4809934 | 4.60 | nM | Homo sapiens | |||
18. | ALA4862372 | 36; GSK097 | Selectivity Index | = | 1000 | ALA4809933 | ||||||
19. | ALA4862372 | 36; GSK097 | pIC50 | = | 7.6 | ALA4809932 | 7.60 | nM | Homo sapiens | |||
20. | ALA4862372 | 36; GSK097 | pIC50 | = | 4.6 | ALA4809931 | 4.60 | nM | Homo sapiens |