| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4864918 | A22 | IC50 | > | 10 | uM | ALA4840634 | nM | Homo sapiens | |||
| 2. | ALA4864918 | A22 | IC50 | > | 10 | uM | ALA4840633 | nM | Homo sapiens | |||
| 3. | ALA4864918 | A22 | IC50 | > | 10 | uM | ALA4840632 | nM | Homo sapiens | |||
| 4. | ALA4864918 | A22 | IC50 | = | 0.14 | nM | ALA4840631 | 9.85 | nM | Homo sapiens | ||
| 5. | ALA4864918 | A22 | F | = | 5.8 | % | ALA4840627 | % | ||||
| 6. | ALA4864918 | A22 | CL | = | 3.56 | L/kg/hr | ALA4840626 | mL.min-1.kg-1 | ||||
| 7. | ALA4864918 | A22 | Vdss | = | 3.21 | L/Kg | ALA4840625 | L.kg-1 | ||||
| 8. | ALA4864918 | A22 | t1/2 | = | 2.26 | hr | ALA4840624 | hr | ||||
| 9. | ALA4864918 | A22 | t1/2 | = | 1.26 | hr | ALA4840623 | hr | ||||
| 10. | ALA4864918 | A22 | AUCt | = | 77.02 | ng/mL.hr | ALA4840622 | ng.hr.mL-1 | ||||
| 11. | ALA4864918 | A22 | AUCt | = | 559.22 | ng/mL.hr | ALA4840621 | ng.hr.mL-1 | ||||
| 12. | ALA4864918 | A22 | Cmax | = | 33.6 | ng/ml | ALA4840620 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA4864918 | A22 | Cmax | = | 694 | ng/ml | ALA4840619 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 14. | ALA4864918 | A22 | CLH | = | 4.4 | ml/min.kg | ALA4840618 | mL.min-1.kg-1 | ||||
| 15. | ALA4864918 | A22 | t1/2 | = | 311.9 | min | ALA4840617 | hr | ||||
| 16. | ALA4864918 | A22 | IC50 | = | 0.53 | nM | ALA4840616 | 9.28 | nM | Rattus norvegicus |
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