| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  GDC-0334 | 1; GDC-0334 | permeability | = | 27.5 | 10^-6 cm/s | ALA4828038 | 10^-6 cm/s | ||||
| 2. | GDC-0334 | 1; GDC-0334 | Ratio | = | 0.37 | ALA4828037 | ||||||
| 3. | GDC-0334 | 1; GDC-0334 | PPB | = | 98.8 | % | ALA4828036 | % | ||||
| 4. | GDC-0334 | 1; GDC-0334 | PPB | = | 99.1 | % | ALA4828035 | % | ||||
| 5. | GDC-0334 | 1; GDC-0334 | t1/2 | = | 9.8 | hr | ALA4828034 | hr | ||||
| 6. | GDC-0334 | 1; GDC-0334 | fVdss | = | 467 | L/Kg | ALA4828033 | L/Kg | ||||
| 7. | GDC-0334 | 1; GDC-0334 | Vdss | = | 5.6 | L/Kg | ALA4828032 | L.kg-1 | ||||
| 8. | GDC-0334 | 1; GDC-0334 | CL free | = | 642 | ml/min.Kg | ALA4828031 | mL.min-1.kg-1 | ||||
| 9. | GDC-0334 | 1; GDC-0334 | CL | = | 7.7 | ml/min.Kg | ALA4828030 | mL.min-1.kg-1 | ||||
| 10. | GDC-0334 | 1; GDC-0334 | Kinetic_solubility | = | 7 | uM | ALA4828024 | nM | ||||
| 11. | GDC-0334 | 1; GDC-0334 | logD | = | 3.8 | ALA4828023 | ||||||
| 12. | GDC-0334 | 1; GDC-0334 | fEC50 | = | 3.7 | nM | ALA4828022 | nM | Rattus norvegicus | |||
| 13. | GDC-0334 | 1; GDC-0334 | IC50 | = | 10 | nM | ALA4828021 | 8.00 | nM | Rattus norvegicus | ||
| 14. | GDC-0334 | 1; GDC-0334 | IC50 | = | 1.6 | nM | ALA4828020 | 8.80 | nM | Homo sapiens |
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