| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4865471 | 25a | Ratio | > | 337 | ALA5158271 | ||||||
| 2. | ALA4865471 | 25a | IC50 | > | 64 | ug ml-1 | ALA5158268 | ug.mL-1 | Chlorocebus sabaeus | |||
| 3. | ALA4865471 | 25a | MIC | = | 0.19 | ug ml-1 | ALA5158267 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 4. | ALA4865471 | 25a | IC50 | = | 0.9 | ug ml-1 | ALA4831718 | ug.mL-1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
| 5. | ALA4865471 | 25a | Ratio | > | 16 | ALA4831717 | ||||||
| 6. | ALA4865471 | 25a | MIC | = | 0.76 | ug ml-1 | ALA4831716 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 7. | ALA4865471 | 25a | MIC | = | 1.52 | ug ml-1 | ALA4831715 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 8. | ALA4865471 | 25a | MIC | = | 12.16 | ug ml-1 | ALA4831714 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 9. | ALA4865471 | 25a | Activity | = | 2.02 | deltalog10CFU | ALA4831713 | deltalog10CFU | Mycobacterium tuberculosis | |||
| 10. | ALA4865471 | 25a | Activity | = | 4.42 | log10CFU | ALA4831711 | log10CFU | Mycobacterium tuberculosis | |||
| 11. | ALA4865471 | 25a | CL | = | 101 | ml/min.kg | ALA4831709 | mL.min-1.kg-1 | ||||
| 12. | ALA4865471 | 25a | MRT | = | 0.2 | hr | ALA4831708 | hr | ||||
| 13. | ALA4865471 | 25a | AUC | = | 833 | ng.hr/ml | ALA4831707 | ng.hr.mL-1 | ||||
| 14. | ALA4865471 | 25a | AUCt | = | 830 | ng.hr/ml | ALA4831706 | ng.hr.mL-1 | ||||
| 15. | ALA4865471 | 25a | Cmax | = | 4555 | ng/ml | ALA4831705 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 16. | ALA4865471 | 25a | beta t1/2 | = | 0.26 | hr | ALA4831704 | hr | ||||
| 17. | ALA4865471 | 25a | F | = | 7.9 | % | ALA4831703 | % | ||||
| 18. | ALA4865471 | 25a | MRT | = | 1.1 | hr | ALA4831702 | hr | ||||
| 19. | ALA4865471 | 25a | AUC | = | 657 | ng.hr/ml | ALA4831701 | ng.hr.mL-1 | ||||
| 20. | ALA4865471 | 25a | AUCt | = | 651 | ng.hr/ml | ALA4831700 | ng.hr.mL-1 |
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