# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4867108 | 21 | EC50 | = | 2.3 | nM | ALA4825945 | 8.64 | nM | Human orthopneumovirus | ||
2. | ALA4867108 | 21 | Cmax | = | 44.3 | ng/ml | ALA4825938 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
3. | ALA4867108 | 21 | Tmax | = | 2 | hr | ALA4825936 | hr | ||||
4. | ALA4867108 | 21 | Tmax | = | 2.1 | hr | ALA4825933 | hr | ||||
5. | ALA4867108 | 21 | t1/2 | = | 0.8 | hr | ALA4825929 | hr | ||||
6. | ALA4867108 | 21 | t1/2 | = | 2.4 | hr | ALA4825926 | hr | ||||
7. | ALA4867108 | 21 | t1/2 | = | 2.4 | hr | ALA4825925 | hr | ||||
8. | ALA4867108 | 21 | CC50 | > | 25000 | nM | ALA4825923 | nM | Homo sapiens | |||
9. | ALA4867108 | 21 | t1/2 | 0 | ALA4825921 | Not Determined | ||||||
10. | ALA4867108 | 21 | t1/2 | 0 | ALA4825920 | Not Determined | ||||||
11. | ALA4867108 | 21 | t1/2 | 0 | ALA4825919 | Not Determined | ||||||
12. | ALA4867108 | 21 | CLH | 0 | ALA4825918 | Not Determined | ||||||
13. | ALA4867108 | 21 | CLH | 0 | ALA4825917 | Not Determined | ||||||
14. | ALA4867108 | 21 | CLH | 0 | ALA4825916 | Not Determined | ||||||
15. | ALA4867108 | 21 | F | = | 13.8 | % | ALA4825915 | % | ||||
16. | ALA4867108 | 21 | Vdss | = | 11 | L/Kg | ALA4825914 | L.kg-1 | ||||
17. | ALA4867108 | 21 | CL | = | 209 | ml/min.kg | ALA4825913 | mL.min-1.kg-1 | ||||
18. | ALA4867108 | 21 | Cmax | = | 44.3 | ng/ml | ALA4825912 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA4867108 | 21 | Ratio | = | 7.5 | ALA4825910 | ||||||
20. | ALA4867108 | 21 | Papp | = | 2.7 | 10^-6 cm/s | ALA4825909 | 10^-6 cm/s |