# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4867556 | 43 | t1/2 | = | 4.4 | hr | ALA4809948 | hr | ||||
2. | ALA4867556 | 43 | Fu | = | 0.738 | ALA4809922 | ||||||
3. | ALA4867556 | 43 | F | = | 54 | % | ALA4809920 | % | ||||
4. | ALA4867556 | 43 | Vdss | = | 5.9 | L/Kg | ALA4809918 | L.kg-1 | ||||
5. | ALA4867556 | 43 | CL | = | 70 | ml/min.kg | ALA4809916 | mL.min-1.kg-1 | ||||
6. | ALA4867556 | 43 | CLH | < | 0.45 | ml/min/g | ALA4809915 | mL.min-1.g-1 | ||||
7. | ALA4867556 | 43 | CLH | < | 0.65 | ml/min/g | ALA4809914 | mL.min-1.g-1 | ||||
8. | ALA4867556 | 43 | CLH | = | 1.87 | ml/min/g | ALA4809913 | mL.min-1.g-1 | ||||
9. | ALA4867556 | 43 | pIC50 | = | 6.9 | ALA4809912 | 6.90 | nM | Homo sapiens | |||
10. | ALA4867556 | 43 | permeability | = | 200 | nm/s | ALA4809911 | nm/s | ||||
11. | ALA4867556 | 43 | solubility | = | 930 | ug ml-1 | ALA4809910 | ug.mL-1 | ||||
12. | ALA4867556 | 43 | logD | = | 3.1 | ALA4809909 | ||||||
13. | ALA4867556 | 43 | Selectivity Index | = | 1000 | ALA4809908 | ||||||
14. | ALA4867556 | 43 | pIC50 | = | 7.5 | ALA4809907 | 7.50 | nM | Homo sapiens | |||
15. | ALA4867556 | 43 | pIC50 | = | 4.5 | ALA4809906 | 4.50 | nM | Homo sapiens |