# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4867584 | 34 | F | = | 33 | % | ALA4844423 | % | ||||
2. | ALA4867584 | 34 | F | 0 | ALA4844422 | Not Determined | % | |||||
3. | ALA4867584 | 34 | AUCt | = | 2550 | hr.ng/ml | ALA4844421 | ng.hr.mL-1 | ||||
4. | ALA4867584 | 34 | AUCt | 0 | ALA4844420 | Not Determined | ||||||
5. | ALA4867584 | 34 | Cmax | = | 134 | ng/ml | ALA4844419 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
6. | ALA4867584 | 34 | Cmax | 0 | ALA4844418 | Not Determined | ||||||
7. | ALA4867584 | 34 | Tmax | = | 4.7 | hr | ALA4844417 | hr | ||||
8. | ALA4867584 | 34 | Vdss | = | 6.8 | L/Kg | ALA4844416 | L.kg-1 | ||||
9. | ALA4867584 | 34 | Vdss | 0 | ALA4844415 | Not Determined | ||||||
10. | ALA4867584 | 34 | CL | = | 3.2 | ml/min.kg | ALA4844414 | mL.min-1.kg-1 | ||||
11. | ALA4867584 | 34 | CL | 0 | ALA4844413 | Not Determined | ||||||
12. | ALA4867584 | 34 | AUCt | = | 2565 | hr.ng/ml | ALA4844412 | ng.hr.mL-1 | ||||
13. | ALA4867584 | 34 | AUCt | 0 | ALA4844411 | Not Determined | ||||||
14. | ALA4867584 | 34 | t1/2 | = | 25.5 | hr | ALA4844410 | hr | ||||
15. | ALA4867584 | 34 | t1/2 | 0 | ALA4844409 | Not Determined | ||||||
16. | ALA4867584 | 34 | IC50 | = | 13 | nM | ALA4844396 | 7.89 | nM | Homo sapiens | ||
17. | ALA4867584 | 34 | IC50 | = | 5 | nM | ALA4844395 | 8.30 | nM | Homo sapiens | ||
18. | ALA4867584 | 34 | Activity | 0 | ALA4844394 | Active | ||||||
19. | ALA4867584 | 34 | Activity | 0 | ALA4844393 | Active | Homo sapiens | |||||
20. | ALA4867584 | 34 | EC90 | = | 10 | nM | ALA4844392 | nM |