# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4868117 | 6m | FC | = | 5 | ALA4836888 | Homo sapiens | |||||
2. | ALA4868117 | 6m | FC | = | 5 | ALA4836887 | Homo sapiens | |||||
3. | ALA4868117 | 6m | INH | 0 | ALA4836886 | Active | % | Homo sapiens | ||||
4. | ALA4868117 | 6m | INH | 0 | ALA4836885 | Active | % | Homo sapiens | ||||
5. | ALA4868117 | 6m | IC50 | = | 49.11 | uM | ALA4836884 | 4.31 | nM | Homo sapiens | ||
6. | ALA4868117 | 6m | INH | = | 23.12 | % | ALA4836883 | % | Homo sapiens | |||
7. | ALA4868117 | 6m | t1/2 | = | 8.3 | hr | ALA4836882 | hr | ||||
8. | ALA4868117 | 6m | Tmax | = | 0.5 | hr | ALA4836881 | hr | ||||
9. | ALA4868117 | 6m | Cmax | = | 11.06 | ng/ml | ALA4836880 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA4868117 | 6m | AUClast | = | 37.24 | hr.ng/ml | ALA4836879 | ng.hr.mL-1 | ||||
11. | ALA4868117 | 6m | Activity | 0 | ALA4836878 | Non-Toxic | ||||||
12. | ALA4868117 | 6m | TGI | = | 56.7 | % | ALA4836877 | % | Homo sapiens | |||
13. | ALA4868117 | 6m | Activity | = | 3.3 | % | ALA4836876 | % | Homo sapiens | |||
14. | ALA4868117 | 6m | Activity | = | 42.3 | % | ALA4836875 | % | Homo sapiens | |||
15. | ALA4868117 | 6m | Activity | = | 13.4 | % | ALA4836874 | % | Homo sapiens | |||
16. | ALA4868117 | 6m | Activity | = | 41 | % | ALA4836873 | % | Homo sapiens | |||
17. | ALA4868117 | 6m | Activity | = | 4.16 | % | ALA4836872 | % | Homo sapiens | |||
18. | ALA4868117 | 6m | Activity | = | 45.9 | % | ALA4836871 | % | Homo sapiens | |||
19. | ALA4868117 | 6m | Activity | = | 34.9 | % | ALA4836870 | % | Homo sapiens | |||
20. | ALA4868117 | 6m | Activity | = | 15 | % | ALA4836869 | % | Homo sapiens |