Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4868170	39	t1/2	=	1.2	hr	ALA4809949		hr
2.	ALA4868170	39	t1/2	=	1.5	hr	ALA4809948		hr
3.	ALA4868170	39	CL free	=	23	ml/min.kg	ALA4809947		mL.min-1.kg-1
4.	ALA4868170	39	CL free	=	142	ml/min.kg	ALA4809946		mL.min-1.kg-1
5.	ALA4868170	39	Fu	=	0.408		ALA4809924
6.	ALA4868170	39	Fu	=	0.201		ALA4809923
7.	ALA4868170	39	F	=	65	%	ALA4809921		%
8.	ALA4868170	39	F	=	17	%	ALA4809920		%
9.	ALA4868170	39	Vdss	=	0.9	L/Kg	ALA4809919		L.kg-1
10.	ALA4868170	39	Vdss	=	2.1	L/Kg	ALA4809918		L.kg-1
11.	ALA4868170	39	CL	=	9.4	ml/min.kg	ALA4809917		mL.min-1.kg-1
12.	ALA4868170	39	CL	=	52	ml/min.kg	ALA4809916		mL.min-1.kg-1
13.	ALA4868170	39	CLH	<	0.45	ml/min/g	ALA4809915		mL.min-1.g-1
14.	ALA4868170	39	CLH	<	0.65	ml/min/g	ALA4809914		mL.min-1.g-1
15.	ALA4868170	39	CLH	=	1.27	ml/min/g	ALA4809913		mL.min-1.g-1
16.	ALA4868170	39	pIC50	=	6.6		ALA4809912	6.60	nM	Homo sapiens
17.	ALA4868170	39	permeability	=	145	nm/s	ALA4809911		nm/s
18.	ALA4868170	39	solubility	=	575	ug ml-1	ALA4809910		ug.mL-1
19.	ALA4868170	39	logD	=	3.4		ALA4809909
20.	ALA4868170	39	Selectivity Index	=	800		ALA4809908