# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4868568 | 24; AS-0141 | INH | = | 36 | % | ALA4831378 | % | ||||
2. | ALA4868568 | 24; AS-0141 | INH | = | 83 | % | ALA4831377 | % | ||||
3. | ALA4868568 | 24; AS-0141 | TGI | = | 83 | % | ALA4831376 | % | Homo sapiens | |||
4. | ALA4868568 | 24; AS-0141 | TGI | = | 88 | % | ALA4831375 | % | Homo sapiens | |||
5. | ALA4868568 | 24; AS-0141 | F | = | 33.3 | % | ALA4831374 | % | ||||
6. | ALA4868568 | 24; AS-0141 | F | = | 54.4 | % | ALA4831373 | % | ||||
7. | ALA4868568 | 24; AS-0141 | F | = | 30.6 | % | ALA4831372 | % | ||||
8. | ALA4868568 | 24; AS-0141 | MRT | = | 5.26 | hr | ALA4831371 | hr | ||||
9. | ALA4868568 | 24; AS-0141 | MRT | = | 1.45 | hr | ALA4831370 | hr | ||||
10. | ALA4868568 | 24; AS-0141 | MRT | = | 0.3 | hr | ALA4831369 | hr | ||||
11. | ALA4868568 | 24; AS-0141 | CL | = | 0.81 | L/hr/kg | ALA4831368 | mL.min-1.kg-1 | ||||
12. | ALA4868568 | 24; AS-0141 | CL | = | 2.26 | L/hr/kg | ALA4831367 | mL.min-1.kg-1 | ||||
13. | ALA4868568 | 24; AS-0141 | CL | = | 6.73 | L/hr/kg | ALA4831366 | mL.min-1.kg-1 | ||||
14. | ALA4868568 | 24; AS-0141 | Vd | = | 4.22 | L/Kg | ALA4831365 | L.kg-1 | ||||
15. | ALA4868568 | 24; AS-0141 | Vd | = | 3.24 | L/Kg | ALA4831364 | L.kg-1 | ||||
16. | ALA4868568 | 24; AS-0141 | Vd | = | 3.1 | L/Kg | ALA4831363 | L.kg-1 | ||||
17. | ALA4868568 | 24; AS-0141 | AUC | = | 834 | ng/mL.hr | ALA4831362 | ng.hr.mL-1 | ||||
18. | ALA4868568 | 24; AS-0141 | AUC | = | 1253 | ng/mL.hr | ALA4831361 | ng.hr.mL-1 | ||||
19. | ALA4868568 | 24; AS-0141 | AUC | = | 2413 | ng/mL.hr | ALA4831360 | ng.hr.mL-1 | ||||
20. | ALA4868568 | 24; AS-0141 | AUC | = | 887 | ng/mL.hr | ALA4831359 | ng.hr.mL-1 |