Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4869149	71; GSK852	t1/2	=	0.7	hr	ALA4836651		hr
2.	ALA4869149	71; GSK852	F	=	64	%	ALA4836650		%
3.	ALA4869149	71; GSK852	t1/2	=	2.9	hr	ALA4836649		hr
4.	ALA4869149	71; GSK852	Vdss	=	0.9	L/Kg	ALA4836648		L.kg-1
5.	ALA4869149	71; GSK852	LBF	=	8	%	ALA4836647		%
6.	ALA4869149	71; GSK852	CL free	=	24	ml/min.kg	ALA4836646		mL.min-1.kg-1
7.	ALA4869149	71; GSK852	CL	=	5	ml/min.kg	ALA4836645		mL.min-1.kg-1
8.	ALA4869149	71; GSK852	F	=	32	%	ALA4836644		%
9.	ALA4869149	71; GSK852	Vdss	=	2.3	L/Kg	ALA4836643		L.kg-1
10.	ALA4869149	71; GSK852	CL free	=	260	ml/min.kg	ALA4836642		mL.min-1.kg-1
11.	ALA4869149	71; GSK852	CL	=	55	ml/min.kg	ALA4836641		mL.min-1.kg-1
12.	ALA4869149	71; GSK852	CLH	<	0.5	ml/min/g	ALA4836640		mL.min-1.g-1
13.	ALA4869149	71; GSK852	CLH	<	0.7	ml/min/g	ALA4836639		mL.min-1.g-1
14.	ALA4869149	71; GSK852	pIC50	=	7.8		ALA4836638	7.80	nM	Homo sapiens
15.	ALA4869149	71; GSK852	pIC50	=	7.7		ALA4836637	7.70	nM
16.	ALA4869149	71; GSK852	Ratio pIC50	=	1300		ALA4836636
17.	ALA4869149	71; GSK852	CLH	=	1	ml/min/g	ALA4836635		mL.min-1.g-1
18.	ALA4869149	71; GSK852	solubility	>	1000	ug ml-1	ALA4836634		ug.mL-1
19.	ALA4869149	71; GSK852	solubility	>=	209	ug ml-1	ALA4836633		ug.mL-1
20.	ALA4869149	71; GSK852	logD	=	3.3		ALA4836632