| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4870360 | 45 | F | = | 30.7 | % | ALA4845023 | % | ||||
| 2. | ALA4870360 | 45 | AUCt/dose | = | 236 | ng/mL.hr | ALA4845022 | ng/mL.hr | ||||
| 3. | ALA4870360 | 45 | Tmax | = | 2.3 | hr | ALA4845021 | hr | ||||
| 4. | ALA4870360 | 45 | Cmax/dose | = | 35 | ng/ml | ALA4845020 | ng/ml | ||||
| 5. | ALA4870360 | 45 | t1/2 | = | 4.8 | hr | ALA4845019 | hr | ||||
| 6. | ALA4870360 | 45 | AUCt/dose | = | 767 | ng/mL.hr | ALA4845018 | ng/mL.hr | ||||
| 7. | ALA4870360 | 45 | Vdss | = | 1.4 | L/Kg | ALA4845017 | L.kg-1 | ||||
| 8. | ALA4870360 | 45 | CL | = | 24.7 | ml/min.Kg | ALA4845016 | mL.min-1.kg-1 | ||||
| 9. | ALA4870360 | 45 | t1/2 | = | 1.2 | hr | ALA4845015 | hr | ||||
| 10. | ALA4870360 | 45 | EC50 | = | 67 | nM | ALA4845014 | 7.17 | nM | Mus musculus | ||
| 11. | ALA4870360 | 45 | EC50 | = | 87 | nM | ALA4845013 | 7.06 | nM | Mus musculus | ||
| 12. | ALA4870360 | 45 | INH | = | 18 | % | ALA4845010 | % | Homo sapiens | |||
| 13. | ALA4870360 | 45 | INH | = | 2 | % | ALA4845009 | % | Homo sapiens | |||
| 14. | ALA4870360 | 45 | IC50 | = | 12.7 | nM | ALA4845008 | 7.90 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!