| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4870367 | 3h | F | = | 80 | % | ALA4835470 | % | ||||
| 2. | ALA4870367 | 3h | t1/2 | = | 3.6 | hr | ALA4835469 | hr | ||||
| 3. | ALA4870367 | 3h | Vdu | = | 0.9 | L/Kg | ALA4835468 | L.kg-1 | ||||
| 4. | ALA4870367 | 3h | Vd | = | 0.6 | L/Kg | ALA4835467 | L.kg-1 | ||||
| 5. | ALA4870367 | 3h | CL | = | 3.3 | ml/min.kg | ALA4835466 | mL.min-1.kg-1 | ||||
| 6. | ALA4870367 | 3h | CL | = | 2.1 | ml/min.kg | ALA4835465 | mL.min-1.kg-1 | ||||
| 7. | ALA4870367 | 3h | F | = | 37 | % | ALA4835462 | % | ||||
| 8. | ALA4870367 | 3h | t1/2 | = | 1.8 | hr | ALA4835461 | hr | ||||
| 9. | ALA4870367 | 3h | Vdu | = | 2.5 | L/Kg | ALA4835460 | L.kg-1 | ||||
| 10. | ALA4870367 | 3h | Vd | = | 0.5 | L/Kg | ALA4835459 | L.kg-1 | ||||
| 11. | ALA4870367 | 3h | CL | = | 19 | ml/min.kg | ALA4835458 | mL.min-1.kg-1 | ||||
| 12. | ALA4870367 | 3h | CL | = | 3.8 | ml/min.kg | ALA4835457 | mL.min-1.kg-1 | ||||
| 13. | ALA4870367 | 3h | logD | = | 1 | ALA4835456 | ||||||
| 14. | ALA4870367 | 3h | Papp | = | 18 | 10^-6 cm/s | ALA4835455 | 10^-6 cm/s | ||||
| 15. | ALA4870367 | 3h | IC50 | = | 75 | nM | ALA4835454 | 7.12 | nM | Homo sapiens | ||
| 16. | ALA4870367 | 3h | IC50 | > | 10 | uM | ALA4835453 | nM | ||||
| 17. | ALA4870367 | 3h | IC50 | = | 110 | nM | ALA4835452 | 6.96 | nM | Homo sapiens | ||
| 18. | ALA4870367 | 3h | Ratio IC50 | = | 480 | ALA4835451 | ||||||
| 19. | ALA4870367 | 3h | IC50 | = | 2.8 | nM | ALA4835450 | 8.55 | nM | Homo sapiens |
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