# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ML792 | ML-792 | F | = | 7.1 | % | ALA4835034 | % | ||||
2. | ML792 | ML-792 | F | = | 6.9 | % | ALA4835033 | % | ||||
3. | ML792 | ML-792 | AUC | = | 0.1 | uM.hr | ALA4835032 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
4. | ML792 | ML-792 | AUC | = | 10.8 | uM.hr | ALA4835031 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
5. | ML792 | ML-792 | t1/2 | = | 0.9 | hr | ALA4835030 | hr | ||||
6. | ML792 | ML-792 | t1/2 | = | 1.2 | hr | ALA4835029 | hr | ||||
7. | ML792 | ML-792 | Vdss | = | 5.1 | L/Kg | ALA4835028 | L.kg-1 | ||||
8. | ML792 | ML-792 | Vdss | = | 0.1 | L/Kg | ALA4835027 | L.kg-1 | ||||
9. | ML792 | ML-792 | CL | = | 5.1 | L.hr/kg | ALA4835026 | mL.min-1.kg-1 | ||||
10. | ML792 | ML-792 | CL | = | 0.1 | L.hr/kg | ALA4835025 | mL.min-1.kg-1 | ||||
11. | ML792 | ML-792 | AUC | = | 0.4 | uM.hr | ALA4835024 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
12. | ML792 | ML-792 | AUC | = | 19.1 | uM.hr | ALA4835023 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
13. | ML792 | ML-792 | IC50 | = | 0.01 | uM | ALA4835022 | 8.00 | nM | Homo sapiens | ||
14. | ML792 | ML-792 | IC50 | = | 0.05 | uM | ALA4835021 | 7.30 | nM | Homo sapiens | ||
15. | ML792 | ML-792 | Ratio | > | 16 | ALA4835019 | ||||||
16. | ML792 | ML-792 | Papp | = | 64 | 10^-6 cm/s | ALA4835018 | 10^-6 cm/s | ||||
17. | ML792 | ML-792 | Papp | = | 1.2 | 10^-6 cm/s | ALA4835017 | 10^-6 cm/s | ||||
18. | ML792 | ML-792 | pKa | = | 3.6 | ALA4835016 | ||||||
19. | ML792 | ML-792 | logD | = | 2.6 | ALA4835015 | ||||||
20. | ML792 | ML-792 | EC50 | = | 0.055 | uM | ALA4835010 | 7.26 | nM | Homo sapiens |