| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4870448 | 40 | F | = | 1.6 | % | ALA4845023 | % | ||||
| 2. | ALA4870448 | 40 | AUCt/dose | = | 15 | ng/mL.hr | ALA4845022 | ng/mL.hr | ||||
| 3. | ALA4870448 | 40 | Tmax | = | 6 | hr | ALA4845021 | hr | ||||
| 4. | ALA4870448 | 40 | Cmax/dose | = | 1.7 | ng/ml | ALA4845020 | ng/ml | ||||
| 5. | ALA4870448 | 40 | t1/2 | = | 6.7 | hr | ALA4845019 | hr | ||||
| 6. | ALA4870448 | 40 | AUCt/dose | = | 1252 | ng/mL.hr | ALA4845018 | ng/mL.hr | ||||
| 7. | ALA4870448 | 40 | Vdss | = | 9 | L/Kg | ALA4845017 | L.kg-1 | ||||
| 8. | ALA4870448 | 40 | CL | = | 16.5 | ml/min.Kg | ALA4845016 | mL.min-1.kg-1 | ||||
| 9. | ALA4870448 | 40 | t1/2 | = | 20.6 | hr | ALA4845015 | hr | ||||
| 10. | ALA4870448 | 40 | EC50 | = | 81 | nM | ALA4845014 | 7.09 | nM | Mus musculus | ||
| 11. | ALA4870448 | 40 | EC50 | = | 91 | nM | ALA4845013 | 7.04 | nM | Mus musculus | ||
| 12. | ALA4870448 | 40 | INH | = | 29 | % | ALA4845010 | % | Homo sapiens | |||
| 13. | ALA4870448 | 40 | INH | = | 6 | % | ALA4845009 | % | Homo sapiens | |||
| 14. | ALA4870448 | 40 | IC50 | = | 12.9 | nM | ALA4845008 | 7.89 | nM | Homo sapiens |
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