# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4870635 | 27 | CLH | = | 27 | microL/min/mg | ALA4812972 | mL.min-1.g-1 | ||||
2. | ALA4870635 | 27 | Activity | 0 | ALA4812971 | Dose-Dependent Effect | Rattus norvegicus | |||||
3. | ALA4870635 | 27 | Activity | 0 | ALA4812970 | Active | Rattus norvegicus | |||||
4. | ALA4870635 | 27 | F | = | 57 | % | ALA4812969 | % | ||||
5. | ALA4870635 | 27 | MRT | = | 4.05 | hr | ALA4812968 | hr | ||||
6. | ALA4870635 | 27 | AUC | = | 1540 | ng/mL.hr | ALA4812967 | ng.hr.mL-1 | ||||
7. | ALA4870635 | 27 | CL | = | 373 | ml/kg/hr | ALA4812966 | mL.min-1.kg-1 | ||||
8. | ALA4870635 | 27 | Vdss | = | 1270 | ml/hr/kg | ALA4812965 | ml/hr/kg | ||||
9. | ALA4870635 | 27 | EC50 | = | 3.8 | nM | ALA4812964 | 8.42 | nM | Rattus norvegicus | ||
10. | ALA4870635 | 27 | EC50 | = | 4.8 | nM | ALA4812963 | 8.32 | nM | Rattus norvegicus | ||
11. | ALA4870635 | 27 | EC50 | = | 24 | nM | ALA4812962 | 7.62 | nM | Rattus norvegicus | ||
12. | ALA4870635 | 27 | solubility | = | 21 | ug ml-1 | ALA4812961 | ug.mL-1 | ||||
13. | ALA4870635 | 27 | CLH | < | 1 | microL/min/mg | ALA4812960 | mL.min-1.g-1 | ||||
14. | ALA4870635 | 27 | CLH | = | 27 | microL/min/mg | ALA4812959 | mL.min-1.g-1 | ||||
15. | ALA4870635 | 27 | INH | = | 19 | % | ALA4812957 | % | Homo sapiens | |||
16. | ALA4870635 | 27 | EC50 | = | 4.6 | nM | ALA4812956 | 8.34 | nM | Homo sapiens |