# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4870834 | 19 | permeability | = | 41 | 10^-6 cm/s | ALA4841575 | 10^-6 cm/s | ||||
2. | ALA4870834 | 19 | t1/2 | > | 200 | hr | ALA4841574 | hr | ||||
3. | ALA4870834 | 19 | F | = | 35.5 | % | ALA4841573 | % | ||||
4. | ALA4870834 | 19 | Vdss | = | 23200 | ml/kg | ALA4841572 | L.kg-1 | ||||
5. | ALA4870834 | 19 | CL | = | 60.7 | ml/min.kg | ALA4841571 | mL.min-1.kg-1 | ||||
6. | ALA4870834 | 19 | t1/2 | = | 5.6 | hr | ALA4841570 | hr | ||||
7. | ALA4870834 | 19 | t1/2 | = | 6.1 | hr | ALA4841569 | hr | ||||
8. | ALA4870834 | 19 | AUC | = | 271 | ng.hr/ml | ALA4841568 | ng.hr.mL-1 | ||||
9. | ALA4870834 | 19 | AUC | = | 264 | ng.hr/ml | ALA4841567 | ng.hr.mL-1 | ||||
10. | ALA4870834 | 19 | Tmax | = | 2.3 | hr | ALA4841566 | hr | ||||
11. | ALA4870834 | 19 | Cmax | = | 32.1 | ng/ml | ALA4841565 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
12. | ALA4870834 | 19 | Activity | = | 12.5 | umol/L | ALA4841564 | umol/L | ||||
13. | ALA4870834 | 19 | IC50 | = | 4.9 | umol/L | ALA4841563 | 5.31 | nM | Homo sapiens | ||
14. | ALA4870834 | 19 | EC50 | = | 0.041 | nmol/L | ALA4841562 | 10.39 | nM | Homo sapiens |