# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4870873 | 18 | Activity | 0 | ALA4831677 | Active | ||||||
2. | ALA4870873 | 18 | Drug uptake | 0 | ALA4831676 | Active | ||||||
3. | ALA4870873 | 18 | Drug uptake | 0 | ALA4831675 | Active | ||||||
4. | ALA4870873 | 18 | Activity | 0 | ALA4831672 | Non-Toxic | ||||||
5. | ALA4870873 | 18 | TGI | = | 30.8 | % | ALA4831671 | % | Homo sapiens | |||
6. | ALA4870873 | 18 | F | > | 100 | % | ALA4831670 | % | ||||
7. | ALA4870873 | 18 | t1/2 | = | 17 | hr | ALA4831669 | hr | ||||
8. | ALA4870873 | 18 | AUC | = | 14.6 | uM.hr | ALA4831668 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
9. | ALA4870873 | 18 | Cmax | = | 2.13 | uM | ALA4831667 | nM | ||||
10. | ALA4870873 | 18 | t1/2 | = | 8.7 | hr | ALA4831666 | hr | ||||
11. | ALA4870873 | 18 | Vdss | = | 4.82 | L/Kg | ALA4831665 | L.kg-1 | ||||
12. | ALA4870873 | 18 | CL | = | 23 | uL/min/kg | ALA4831664 | mL.min-1.kg-1 | ||||
13. | ALA4870873 | 18 | CLH | = | 249 | microL/min/mg | ALA4831663 | mL.min-1.g-1 | ||||
14. | ALA4870873 | 18 | CLH | = | 59 | microL/min/mg | ALA4831662 | mL.min-1.g-1 | ||||
15. | ALA4870873 | 18 | PPB | > | 99.6 | % | ALA4831661 | % | ||||
16. | ALA4870873 | 18 | Papp | < | 0.1 | 10^-6 cm/s | ALA4831660 | 10^-6 cm/s | ||||
17. | ALA4870873 | 18 | solubility | < | 0.2 | uM | ALA4831659 | nM | ||||
18. | ALA4870873 | 18 | GI50 | > | 10 | uM | ALA4831658 | nM | Homo sapiens | |||
19. | ALA4870873 | 18 | GI50 | > | 10 | uM | ALA4831657 | nM | Homo sapiens | |||
20. | ALA4870873 | 18 | GI50 | = | 40.9 | nM | ALA4831656 | nM | Homo sapiens |