# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4871481 | 37 | fIC50 | = | 1 | nM | ALA4836100 | nM | Homo sapiens | |||
2. | ALA4871481 | 37 | INH | = | 23 | % | ALA4836094 | % | Homo sapiens | |||
3. | ALA4871481 | 37 | INH | = | 58 | % | ALA4836093 | % | Homo sapiens | |||
4. | ALA4871481 | 37 | INH | = | 61 | % | ALA4836092 | % | Homo sapiens | |||
5. | ALA4871481 | 37 | Therm_solubility | = | 36 | ug ml-1 | ALA4836091 | ug.mL-1 | ||||
6. | ALA4871481 | 37 | Therm_solubility | = | 5 | ug ml-1 | ALA4836090 | ug.mL-1 | ||||
7. | ALA4871481 | 37 | PPB | = | 98.4 | % | ALA4836089 | % | ||||
8. | ALA4871481 | 37 | PPB | = | 99.9 | % | ALA4836088 | % | ||||
9. | ALA4871481 | 37 | PPB | = | 99.8 | % | ALA4836087 | % | ||||
10. | ALA4871481 | 37 | F | = | 30 | % | ALA4836084 | % | ||||
11. | ALA4871481 | 37 | F | = | 10 | % | ALA4836083 | % | ||||
12. | ALA4871481 | 37 | F | = | 20 | % | ALA4836082 | % | ||||
13. | ALA4871481 | 37 | Vdss | = | 2.1 | L/Kg | ALA4836081 | L.kg-1 | ||||
14. | ALA4871481 | 37 | Vdss | = | 0.38 | L/Kg | ALA4836080 | L.kg-1 | ||||
15. | ALA4871481 | 37 | Vdss | = | 0.49 | L/Kg | ALA4836079 | L.kg-1 | ||||
16. | ALA4871481 | 37 | CL | = | 0.47 | L/hr/kg | ALA4836078 | mL.min-1.kg-1 | ||||
17. | ALA4871481 | 37 | CL | = | 0.25 | L/hr/kg | ALA4836077 | mL.min-1.kg-1 | ||||
18. | ALA4871481 | 37 | CL | = | 0.62 | L/hr/kg | ALA4836076 | mL.min-1.kg-1 | ||||
19. | ALA4871481 | 37 | t1/2 | = | 3.1 | hr | ALA4836075 | hr | ||||
20. | ALA4871481 | 37 | t1/2 | = | 1.1 | hr | ALA4836074 | hr |