# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4871566 | 58-2TFA | Activity | 0 | ALA5133927 | Non-Toxic | Homo sapiens | |||||
2. | ALA4871566 | 58-2TFA | solubility | > | 13 | mM | ALA5133926 | nM | ||||
3. | ALA4871566 | 58-2TFA | CC50 | > | 300 | uM | ALA5133925 | nM | Homo sapiens | |||
4. | ALA4871566 | 58-2TFA | IC50 | = | 6.7 | uM | ALA5133924 | 5.17 | nM | Human immunodeficiency virus 1 | ||
5. | ALA4871566 | 58-2TFA | Activity | 0 | ALA4815092 | Toxic | ||||||
6. | ALA4871566 | 58-2TFA | Activity | 0 | ALA4815091 | Toxic | ||||||
7. | ALA4871566 | 58-2TFA | AUC | = | 10400 | mg.hr/L | ALA4815090 | ng.hr.mL-1 | ||||
8. | ALA4871566 | 58-2TFA | AUC | = | 14400 | mg.hr/L | ALA4815089 | ng.hr.mL-1 | ||||
9. | ALA4871566 | 58-2TFA | AUC | = | 33600 | mg.hr/L | ALA4815088 | ng.hr.mL-1 | ||||
10. | ALA4871566 | 58-2TFA | AUC | = | 11000 | mg.hr/L | ALA4815087 | ng.hr.mL-1 | ||||
11. | ALA4871566 | 58-2TFA | Vd | = | 114 | ml | ALA4815086 | ml | ||||
12. | ALA4871566 | 58-2TFA | Vd | = | 215 | ml | ALA4815085 | ml | ||||
13. | ALA4871566 | 58-2TFA | Vd | = | 200 | ml | ALA4815084 | ml | ||||
14. | ALA4871566 | 58-2TFA | Vd | = | 592 | ml | ALA4815083 | ml | ||||
15. | ALA4871566 | 58-2TFA | Cmax | = | 56.4 | uM | ALA4815082 | nM | ||||
16. | ALA4871566 | 58-2TFA | Cmax | = | 59.4 | uM | ALA4815081 | nM | ||||
17. | ALA4871566 | 58-2TFA | Cmax | = | 128 | uM | ALA4815080 | nM | ||||
18. | ALA4871566 | 58-2TFA | Cmax | = | 39.5 | uM | ALA4815079 | nM | ||||
19. | ALA4871566 | 58-2TFA | t1/2 | = | 47.6 | min | ALA4815078 | hr | ||||
20. | ALA4871566 | 58-2TFA | t1/2 | = | 58.9 | min | ALA4815077 | hr |