| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4871593 | 16 | IC50 | = | 75 | nM | ALA4844353 | 7.12 | nM | Homo sapiens | ||
| 2. | ALA4871593 | 16 | AUC | = | 45 | uM.hr | ALA4844352 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 3. | ALA4871593 | 16 | Activity | 0 | ALA4844351 | Active | Homo sapiens | |||||
| 4. | ALA4871593 | 16 | F | = | 142 | % | ALA4844350 | % | ||||
| 5. | ALA4871593 | 16 | Vdss | = | 4.4 | L/Kg | ALA4844349 | L.kg-1 | ||||
| 6. | ALA4871593 | 16 | t1/2 | = | 2.3 | hr | ALA4844348 | hr | ||||
| 7. | ALA4871593 | 16 | t1/2 | = | 1.4 | hr | ALA4844347 | hr | ||||
| 8. | ALA4871593 | 16 | Cmax | = | 2.1 | uM | ALA4844346 | nM | ||||
| 9. | ALA4871593 | 16 | CL | = | 46 | ml/min.kg | ALA4844345 | mL.min-1.kg-1 | ||||
| 10. | ALA4871593 | 16 | AUC | = | 9.7 | uM.hr | ALA4844344 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 11. | ALA4871593 | 16 | AUC | = | 2.1 | uM.hr | ALA4844343 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 12. | ALA4871593 | 16 | IC50 | > | 30 | uM | ALA4844342 | nM | Homo sapiens | |||
| 13. | ALA4871593 | 16 | CLH | < | 18 | ml/min.kg | ALA4844341 | mL.min-1.kg-1 | ||||
| 14. | ALA4871593 | 16 | Therm_solubility | = | 2132 | uM | ALA4844340 | nM | ||||
| 15. | ALA4871593 | 16 | Ratio IC50 | > | 10 | ALA4844339 | ||||||
| 16. | ALA4871593 | 16 | Ratio IC50 | > | 10 | ALA4844338 | ||||||
| 17. | ALA4871593 | 16 | Ratio IC50 | > | 10 | ALA4844337 | ||||||
| 18. | ALA4871593 | 16 | Ratio IC50 | > | 10 | ALA4844336 | ||||||
| 19. | ALA4871593 | 16 | Ratio IC50 | > | 10 | ALA4844335 | ||||||
| 20. | ALA4871593 | 16 | IC50 | = | 70 | nM | ALA4844334 | 7.16 | nM | Homo sapiens |
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