# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4872328 | 9 | Drug metabolism | 0 | ALA4828209 | Metabolite_Detected | ||||||
2. | ALA4872328 | 9 | t1/2 | = | 1 | hr | ALA4828208 | hr | ||||
3. | ALA4872328 | 9 | Vdss | = | 0.3 | L/Kg | ALA4828207 | L.kg-1 | ||||
4. | ALA4872328 | 9 | CL | = | 8.6 | ml/min.kg | ALA4828206 | mL.min-1.kg-1 | ||||
5. | ALA4872328 | 9 | CLH | < | 0.4 | ml/min.kg | ALA4828205 | mL.min-1.kg-1 | ||||
6. | ALA4872328 | 9 | CLH | = | 0.54 | ml/min.kg | ALA4828204 | mL.min-1.kg-1 | ||||
7. | ALA4872328 | 9 | logD | = | 1.8 | ALA4828203 | ||||||
8. | ALA4872328 | 9 | solubility | > | 1 | mg/ml | ALA4828202 | ug.mL-1 | ||||
9. | ALA4872328 | 9 | pIC50 | < | 4.3 | ALA4828201 | nM | Homo sapiens | ||||
10. | ALA4872328 | 9 | Ratio IC50 | = | 63 | ALA4828200 | ||||||
11. | ALA4872328 | 9 | pIC50 | = | 7 | ALA4828199 | 7.00 | nM | Homo sapiens | |||
12. | ALA4872328 | 9 | pIC50 | = | 8.8 | ALA4828198 | 8.80 | nM | Homo sapiens | |||
13. | ALA4872328 | 9 | Ratio IC50 | >= | 1000 | ALA4828197 | ||||||
14. | ALA4872328 | 9 | Ratio IC50 | >= | 1000 | ALA4828196 | ||||||
15. | ALA4872328 | 9 | Ratio IC50 | >= | 1000 | ALA4828195 | ||||||
16. | ALA4872328 | 9 | PB | = | 83 | % | ALA4828193 | % | Homo sapiens | |||
17. | ALA4872328 | 9 | pIC50 | = | 7.3 | ALA4828192 | 7.30 | nM | Homo sapiens | |||
18. | ALA4872328 | 9 | pIC50 | = | 4.6 | ALA4828191 | 4.60 | nM | Homo sapiens | |||
19. | ALA4872328 | 9 | pIC50 | = | 5.3 | ALA4828190 | 5.30 | nM | Homo sapiens | |||
20. | ALA4872328 | 9 | pIC50 | = | 5.3 | ALA4828189 | 5.30 | nM | Homo sapiens |