| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4872490 | 30 | Drug metabolism | = | 43.6 | pmol/min | ALA4809551 | pmol/min | Homo sapiens | |||
| 2. | ALA4872490 | 30 | Drug metabolism | = | 42.6 | pmol/min | ALA4809550 | pmol/min | Homo sapiens | |||
| 3. | ALA4872490 | 30 | Drug metabolism | = | 15.4 | pmol/min | ALA4809549 | pmol/min | Homo sapiens | |||
| 4. | ALA4872490 | 30 | F | = | 38 | % | ALA4809548 | % | ||||
| 5. | ALA4872490 | 30 | t1/2 | = | 6.5 | hr | ALA4809547 | hr | ||||
| 6. | ALA4872490 | 30 | t1/2 | = | 3.2 | hr | ALA4809546 | hr | ||||
| 7. | ALA4872490 | 30 | AUC | = | 1008 | hr.ng/ml | ALA4809545 | ng.hr.mL-1 | ||||
| 8. | ALA4872490 | 30 | AUC | = | 544 | hr.ng/ml | ALA4809544 | ng.hr.mL-1 | ||||
| 9. | ALA4872490 | 30 | Cmax | = | 226 | mg/ml | ALA4809543 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA4872490 | 30 | Cmax | = | 250 | mg/ml | ALA4809542 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA4872490 | 30 | Tmax | = | 1.5 | hr | ALA4809541 | hr | ||||
| 12. | ALA4872490 | 30 | Tmax | = | 0.17 | hr | ALA4809540 | hr | ||||
| 13. | ALA4872490 | 30 | t1/2 | > | 15 | day | ALA4809539 | hr | ||||
| 14. | ALA4872490 | 30 | t1/2 | > | 30 | day | ALA4809538 | hr | ||||
| 15. | ALA4872490 | 30 | Ratio IC50 | = | 36.1 | ALA4809533 | ||||||
| 16. | ALA4872490 | 30 | IC50 | = | 37.5 | uM | ALA4809531 | 4.43 | nM | |||
| 17. | ALA4872490 | 30 | IC50 | = | 34.2 | uM | ALA4809530 | 4.47 | nM | |||
| 18. | ALA4872490 | 30 | IC50 | = | 1.04 | uM | ALA4809529 | 5.98 | nM | |||
| 19. | ALA4872490 | 30 | EC50 | 0 | ALA4809526 | Not Active | ||||||
| 20. | ALA4872490 | 30 | Activity | 0 | ALA4809525 | Not Active |
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